|Title||Obstructive airway disease and edentulism in the atherosclerosis risk in communities (ARIC) study.|
|Publication Type||Journal Article|
|Year of Publication||2012|
|Authors||Offenbacher S, Beck JD, Barros SP, Suruki RY, Loewy ZG|
OBJECTIVES: We examined the potential association between prior chronic obstructive pulmonary disease (COPD) and edentulism, and whether the association varied by COPD severity using data from the Dental Atherosclerosis Risk in Communities Study.
SETTING: Community dwelling subjects from four US communities.
PARTICIPANTS AND MEASUREMENTS: Cases were identified as edentulous (without teeth) and subjects with one or more natural teeth were identified as dentate. COPD cases were defined by spirometry measurements that showed the ratio of forced expiratory volume (1 s) to vital capacity to be less than 0.7. The severity of COPD cases was also determined using a modified Global Initiative for Chronic Obstructive Lung Disease classification criteria (GOLD stage I-IV). Multiple logistic regression was used to examine the association between COPD and edentulism, while adjusting for age, gender, centre/race, ethnicity, education level, income, diabetes, hypertension, coronary heart disease and congestive heart failure, body mass index, smoking, smokeless tobacco use and alcohol consumption.
RESULTS: 13 465 participants were included in this analysis (2087 edentulous; 11 378 dentate). Approximately 28.3% of edentulous participants had prior COPD compared with 19.6% among dentate participants (p
CONCLUSIONS: We found a statistically significant association between prior COPD and edentulism, with evidence of a positive incremental effect seen with increasing GOLD classification.
|Alternate Journal||BMJ Open|
|PubMed Central ID||PMC3533002|
|Grant List||R01 DE011551 / DE / NIDCR NIH HHS / United States |
T32 DE007310 / DE / NIDCR NIH HHS / United States
UL1 RR025747 / RR / NCRR NIH HHS / United States