Title | Ideal cardiovascular health is inversely associated with incident cancer: the Atherosclerosis Risk In Communities study. |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | Rasmussen-Torvik LJ, Shay CM, Abramson JG, Friedrich CA, Nettleton JA, Prizment AE, Folsom AR |
Journal | Circulation |
Volume | 127 |
Issue | 12 |
Pagination | 1270-5 |
Date Published | 2013 Mar 26 |
ISSN | 1524-4539 |
Keywords | American Heart Association, Cardiovascular Diseases, Cardiovascular Physiological Phenomena, Female, Follow-Up Studies, Humans, Incidence, Male, Middle Aged, Neoplasms, Proportional Hazards Models, Prospective Studies, Retrospective Studies, Risk Factors, United States |
Abstract | BACKGROUND: The American Heart Association (AHA) has defined the concept of ideal cardiovascular health in promotion of the 2020 Strategic Impact Goals. We examined whether adherence to ideal levels of the 7 AHA cardiovascular health metrics was associated with incident cancers in the Atherosclerosis Risk In Communities (ARIC) study over 17 to 19 years of follow-up. METHODS AND RESULTS: After exclusions for missing data and prevalent cancer, 13 253 ARIC participants were included for analysis. Baseline measurements were used to classify participants according to 7 AHA cardiovascular health metrics. Combined cancer incidence (excluding nonmelanoma skin cancers) from 1987 to 2006 was captured using cancer registries and hospital surveillance; 2880 incident cancer cases occurred over follow-up. Cox regression was used to calculate hazard ratios for incident cancer. There was a significant (P trend CONCLUSIONS: Adherence to the 7 ideal health metrics defined in the AHA 2020 goals is associated with lower cancer incidence. The AHA should continue to pursue partnerships with cancer advocacy groups to achieve reductions in chronic disease prevalence. |
DOI | 10.1161/CIRCULATIONAHA.112.001183 |
Alternate Journal | Circulation |
PubMed ID | 23509058 |
PubMed Central ID | PMC3685848 |
Grant List | HHSN268201100012C / HL / NHLBI NIH HHS / United States HHSN268201100009I / HL / NHLBI NIH HHS / United States HHSN268201100008C / HL / NHLBI NIH HHS / United States HHSN268201100007C / HL / NHLBI NIH HHS / United States HHSN268201100011I / HL / NHLBI NIH HHS / United States HHSN268201100011C / HL / NHLBI NIH HHS / United States HHSN268201100006C / HL / NHLBI NIH HHS / United States HHSN268201100005I / HL / NHLBI NIH HHS / United States HHSN268201100007I / HL / NHLBI NIH HHS / United States UL1 TR000150 / TR / NCATS NIH HHS / United States HHSN268201100010C / HL / NHLBI NIH HHS / United States HHSN268201100005G / HL / NHLBI NIH HHS / United States KL2 TR000107 / TR / NCATS NIH HHS / United States HHSN268201100008I / HL / NHLBI NIH HHS / United States HHSN268201100009C / HL / NHLBI NIH HHS / United States HHSN268201100005C / HL / NHLBI NIH HHS / United States |