| Title | Race- and sex-associated differences in rate-adjusted QT, QTpeak, ST elevation and other regional measures of repolarization: the Atherosclerosis Risk in Communities (ARIC) Study. |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Rautaharju PM, Zhang Z-M, Haisty WK, Gregg RE, Warren J, Horaĉek MB, Kucharska-Newton AMaria, Rosamond WD |
| Secondary Authors | Soliman EZ |
| Journal | J Electrocardiol |
| Volume | 47 |
| Issue | 3 |
| Pagination | 342-50 |
| Date Published | 2014 May-Jun |
| ISSN | 1532-8430 |
| Keywords | Adult, African Americans, Arrhythmias, Cardiac, Comorbidity, Coronary Artery Disease, Electrocardiography, European Continental Ancestry Group, Female, Humans, Incidence, Male, Middle Aged, Prognosis, Reproducibility of Results, Risk Assessment, Sensitivity and Specificity, Sex Distribution |
| Abstract | BACKGROUND: Data are limited about race-and sex-associated differences in prognostically important ECG measures of regional repolarization. METHODS AND RESULTS: The normal reference group from the Atherosclerosis Risk in Communities (ARIC) study included 8,676 white and African-American men and women aged 40-65 years. Exclusion criteria included cardiovascular disease, hypertension, diabetes and major ECG abnormalities. Notable sex differences (p CONCLUSIONS: Shorter QTea and RTepi in men than in women reflect earlier onset and end of repolarization in men. STJ amplitudes in African-American men were higher than in other subgroups by race and sex. These sex and race differences need to be considered in clinical and epidemiological applications of normal standards. |
| DOI | 10.1016/j.jelectrocard.2014.01.012 |
| Alternate Journal | J Electrocardiol |
| PubMed ID | 24607066 |
| Grant List | HHSN268201100005C / / PHS HHS / United States HHSN268201100006C / / PHS HHS / United States HHSN268201100007C / / PHS HHS / United States HHSN268201100008C / / PHS HHS / United States HHSN268201100009C / / PHS HHS / United States HHSN268201100010C / / PHS HHS / United States HHSN268201100011C / / PHS HHS / United States HHSN268201100012C / / PHS HHS / United States |