Title | Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study. |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Schneider ALC, Sharrett ARichey, Gottesman RF, Coresh JJ, Coker L, Wruck L, Selnes OA, Deal J, Knopman D |
Secondary Authors | Mosley TH |
Journal | Alzheimer Dis Assoc Disord |
Volume | 29 |
Issue | 1 |
Pagination | 32-44 |
Date Published | 2015 Jan-Mar |
ISSN | 1546-4156 |
Keywords | African Americans, Aged, Aged, 80 and over, Atherosclerosis, Cohort Studies, European Continental Ancestry Group, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Prospective Studies, Residence Characteristics, Risk Factors |
Abstract | Accurate assessment of cognitive impairment requires comparison of cognitive performance in individuals to performance in a comparable healthy normative population. Few prior studies have included a large number of black participants and few have excluded participants from the normative sample with subclinical/latent neurological disease or dementia. This study provides age, race, and education-specific normative data for 8 cognitive tests derived from 320 black and 392 white participants aged 61 to 82 years (mean 71 y) in the Atherosclerosis Risk in Communities (ARIC) study without clinical or subclinical/latent neurological disease. Normative data are provided for the Delayed Word Recall Test, Logical Memory Parts I and II, the Word Fluency Test, Animal Naming, the Trail Making Test Parts A and B and the Digit Symbol Substitution Test. Age, race, and education-specific mean and -1.5 SD scores are given in tabular form and graphically, as well as regression-based equations to derive adjusted score cut-points. These robust normative data should enhance comparison across studies of cognitive aging, where these measures are widely used, and improve interpretation of performance on these tests for the diagnosis of cognitive impairment not only within the ARIC cohort, but also among older blacks and whites with similar demographics. |
DOI | 10.1097/WAD.0000000000000042 |
Alternate Journal | Alzheimer Dis Assoc Disord |
PubMed ID | 24759546 |
PubMed Central ID | PMC4206681 |
Grant List | HHSN268201100012C / HL / NHLBI NIH HHS / United States U01 HL096812 / HL / NHLBI NIH HHS / United States HHSN268201100010C / HL / NHLBI NIH HHS / United States HHSN268201100008C / HL / NHLBI NIH HHS / United States HHSN268201100007C / HL / NHLBI NIH HHS / United States HHSN268201100011I / HL / NHLBI NIH HHS / United States HHSN268201100011C / HL / NHLBI NIH HHS / United States T32 HL007024 / HL / NHLBI NIH HHS / United States HHSN268201100006C / HL / NHLBI NIH HHS / United States HHSN268201100005I / HL / NHLBI NIH HHS / United States T32HL007024 / HL / NHLBI NIH HHS / United States HHSN268201100007I / HL / NHLBI NIH HHS / United States HHSN268201100005G / HL / NHLBI NIH HHS / United States HHSN268201100008I / HL / NHLBI NIH HHS / United States R01 HL070825 / HL / NHLBI NIH HHS / United States HHSN268201100005C / HL / NHLBI NIH HHS / United States |