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Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study.

TitleNormative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study.
Publication TypeJournal Article
Year of Publication2015
AuthorsSchneider ALC, Sharrett ARichey, Gottesman RF, Coresh JJ, Coker L, Wruck L, Selnes OA, Deal J, Knopman D
Secondary AuthorsMosley TH
JournalAlzheimer Dis Assoc Disord
Volume29
Issue1
Pagination32-44
Date Published2015 Jan-Mar
ISSN1546-4156
KeywordsAfrican Americans, Aged, Aged, 80 and over, Atherosclerosis, Cohort Studies, European Continental Ancestry Group, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Prospective Studies, Residence Characteristics, Risk Factors
Abstract

Accurate assessment of cognitive impairment requires comparison of cognitive performance in individuals to performance in a comparable healthy normative population. Few prior studies have included a large number of black participants and few have excluded participants from the normative sample with subclinical/latent neurological disease or dementia. This study provides age, race, and education-specific normative data for 8 cognitive tests derived from 320 black and 392 white participants aged 61 to 82 years (mean 71 y) in the Atherosclerosis Risk in Communities (ARIC) study without clinical or subclinical/latent neurological disease. Normative data are provided for the Delayed Word Recall Test, Logical Memory Parts I and II, the Word Fluency Test, Animal Naming, the Trail Making Test Parts A and B and the Digit Symbol Substitution Test. Age, race, and education-specific mean and -1.5 SD scores are given in tabular form and graphically, as well as regression-based equations to derive adjusted score cut-points. These robust normative data should enhance comparison across studies of cognitive aging, where these measures are widely used, and improve interpretation of performance on these tests for the diagnosis of cognitive impairment not only within the ARIC cohort, but also among older blacks and whites with similar demographics.

DOI10.1097/WAD.0000000000000042
Alternate JournalAlzheimer Dis Assoc Disord
PubMed ID24759546
PubMed Central IDPMC4206681
Grant ListHHSN268201100012C / HL / NHLBI NIH HHS / United States
U01 HL096812 / HL / NHLBI NIH HHS / United States
HHSN268201100010C / HL / NHLBI NIH HHS / United States
HHSN268201100008C / HL / NHLBI NIH HHS / United States
HHSN268201100007C / HL / NHLBI NIH HHS / United States
HHSN268201100011I / HL / NHLBI NIH HHS / United States
HHSN268201100011C / HL / NHLBI NIH HHS / United States
T32 HL007024 / HL / NHLBI NIH HHS / United States
HHSN268201100006C / HL / NHLBI NIH HHS / United States
HHSN268201100005I / HL / NHLBI NIH HHS / United States
T32HL007024 / HL / NHLBI NIH HHS / United States
HHSN268201100007I / HL / NHLBI NIH HHS / United States
HHSN268201100005G / HL / NHLBI NIH HHS / United States
HHSN268201100008I / HL / NHLBI NIH HHS / United States
R01 HL070825 / HL / NHLBI NIH HHS / United States
HHSN268201100005C / HL / NHLBI NIH HHS / United States