Title | Validity of self-report of lipid medication use: the Atherosclerosis Risk in Communities (ARIC) Study. |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Bhaskara S, Whitsel EA, Ballantyne CM |
Secondary Authors | Folsom AR |
Journal | Atherosclerosis |
Volume | 242 |
Issue | 2 |
Pagination | 625-9 |
Date Published | 2015 Oct |
ISSN | 1879-1484 |
Keywords | Aged, Aged, 80 and over, Atherosclerosis, Female, Follow-Up Studies, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Lipids, Male, Middle Aged, Odds Ratio, Predictive Value of Tests, Prevalence, Prospective Studies, Reproducibility of Results, Self Report, Sensitivity and Specificity, Surveys and Questionnaires, United States |
Abstract | OBJECTIVE: To evaluate the validity of self-reported lipid medication use in an epidemiological study. METHODS: We studied medication self-reports compared with inventoried lipid medication containers at the fifth visit of the Atherosclerosis Risk in Communities (ARIC) Study in 2011-2013 (n = 6370). To assess the validity of self-reports, we computed sensitivity, specificity, positive and negative predictive values. We used multiple logistic regression to determine whether validity varied by participant characteristics. Comparisons were made with visit 4 (n = 11,531), to determine if there was a change in validity as the pattern and types of lipid medication used changed over time. RESULTS: The prevalence of lipid medication use, according to medication containers was higher at visit 5 (56%) than visit 4 (14.3%). Statins were increasingly used. The percentage of participants reporting use/non-use accurately was 91.8% at visit 5, lower than visit 4 (97.3%). The unadjusted kappa coefficient of agreement was 0.83 (95% CI - 0.82 to 0.85) at visit 5 and 0.89 (95% CI - 0.88 to 0.90) at visit 4. Agreement was higher, compared with their counterparts, for women, younger and more educated participants, and those using fewer total medications. CONCLUSION: In this population sample, self-reported lipid medication use was highly accurate and therefore likely would be for similar epidemiological studies or clinical settings collecting this information. |
DOI | 10.1016/j.atherosclerosis.2015.08.026 |
Alternate Journal | Atherosclerosis |
PubMed ID | 26342332 |
PubMed Central ID | PMC4575898 |
Grant List | HHSN268201100012C / HL / NHLBI NIH HHS / United States HHSN268201100010C / HL / NHLBI NIH HHS / United States HHSN268201100008C / HL / NHLBI NIH HHS / United States HHSN268201100005C / / PHS HHS / United States HHSN268201100007C / HL / NHLBI NIH HHS / United States HHSN268201100009C / / PHS HHS / United States HHSN268201100011C / HL / NHLBI NIH HHS / United States HHSN268201100010C / / PHS HHS / United States HHSN268201100006C / HL / NHLBI NIH HHS / United States HHSN268201100008C / / PHS HHS / United States HHSN268201100012C / / PHS HHS / United States HHSN268201100007C / / PHS HHS / United States HHSN268201100009C / HL / NHLBI NIH HHS / United States HHSN268201100011C / / PHS HHS / United States HHSN268201100005C / HL / NHLBI NIH HHS / United States HHSN268201100006C / / PHS HHS / United States |