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Lower Extremity Peripheral Artery Disease and Quality of Life Among Older Individuals in the Community.

TitleLower Extremity Peripheral Artery Disease and Quality of Life Among Older Individuals in the Community.
Publication TypeJournal Article
Year of Publication2017
AuthorsWu A, Coresh JJ, Selvin E, Tanaka H, Heiss G, Hirsch AT, Jaar BG
Secondary AuthorsMatsushita K
JournalJ Am Heart Assoc
Volume6
Issue1
Date Published2017 01 20
ISSN2047-9980
KeywordsActivities of Daily Living, Aged, Aged, 80 and over, Ankle Brachial Index, Cohort Studies, Female, Humans, Independent Living, Linear Models, Logistic Models, Lower Extremity, Male, Mental Health, Pain, Peripheral Arterial Disease, Quality of Life, Role, Severity of Illness Index
Abstract

BACKGROUND: Evidence regarding the association of lower extremity peripheral arterial disease with quality of life (QOL) is mainly from selected clinical populations or relatively small clinical cohorts. Thus, we investigated this association in community-derived populations.

METHODS AND RESULTS: Using data of 5115 participants aged 66 to 90 years from visit 5 (2011-2013) of the Atherosclerosis Risk in Communities Study, we quantified the associations of ankle-brachial index (ABI) with several QOL parameters, including 12-item Short-Form Health Survey (SF-12), after accounting for potential confounders using linear and logistic regression models. Peripheral arterial disease defined by an ABI

CONCLUSIONS: Low ABI (even borderline) was independently associated with poor QOL, especially for physical components, in community-dwelling older adults. QOL is a critical element for older adults, and thus, further studies are warranted to assess whether peripheral arterial disease-specific management can improve QOL in older populations.

DOI10.1161/JAHA.116.004519
Alternate JournalJ Am Heart Assoc
PubMed ID28108464
PubMed Central IDPMC5523635
Grant ListK24 DK106414 / DK / NIDDK NIH HHS / United States
R01 AG053938 / AG / NIA NIH HHS / United States
R01 DK089174 / DK / NIDDK NIH HHS / United States
HHSN268201100005C / HL / NHLBI NIH HHS / United States
HHSN268201100006C / HL / NHLBI NIH HHS / United States
HHSN268201100007C / HL / NHLBI NIH HHS / United States
HHSN268201100008C / HL / NHLBI NIH HHS / United States
HHSN268201100009C / HL / NHLBI NIH HHS / United States
HHSN268201100010C / HL / NHLBI NIH HHS / United States
HHSN268201100011C / HL / NHLBI NIH HHS / United States
HHSN268201100012C / HL / NHLBI NIH HHS / United States