Title | Lower Extremity Peripheral Artery Disease and Quality of Life Among Older Individuals in the Community. |
Publication Type | Journal Article |
Year of Publication | 2017 |
Authors | Wu A, Coresh JJ, Selvin E, Tanaka H, Heiss G, Hirsch AT, Jaar BG |
Secondary Authors | Matsushita K |
Journal | J Am Heart Assoc |
Volume | 6 |
Issue | 1 |
Date Published | 2017 01 20 |
ISSN | 2047-9980 |
Keywords | Activities of Daily Living, Aged, Aged, 80 and over, Ankle Brachial Index, Cohort Studies, Female, Humans, Independent Living, Linear Models, Logistic Models, Lower Extremity, Male, Mental Health, Pain, Peripheral Arterial Disease, Quality of Life, Role, Severity of Illness Index |
Abstract | BACKGROUND: Evidence regarding the association of lower extremity peripheral arterial disease with quality of life (QOL) is mainly from selected clinical populations or relatively small clinical cohorts. Thus, we investigated this association in community-derived populations. METHODS AND RESULTS: Using data of 5115 participants aged 66 to 90Â years from visit 5 (2011-2013) of the Atherosclerosis Risk in Communities Study, we quantified the associations of ankle-brachial index (ABI) with several QOL parameters, including 12-item Short-Form Health Survey (SF-12), after accounting for potential confounders using linear and logistic regression models. Peripheral arterial disease defined by an ABI CONCLUSIONS: Low ABI (even borderline) was independently associated with poor QOL, especially for physical components, in community-dwelling older adults. QOL is a critical element for older adults, and thus, further studies are warranted to assess whether peripheral arterial disease-specific management can improve QOL in older populations. |
DOI | 10.1161/JAHA.116.004519 |
Alternate Journal | J Am Heart Assoc |
PubMed ID | 28108464 |
PubMed Central ID | PMC5523635 |
Grant List | K24 DK106414 / DK / NIDDK NIH HHS / United States R01 AG053938 / AG / NIA NIH HHS / United States R01 DK089174 / DK / NIDDK NIH HHS / United States HHSN268201100005C / HL / NHLBI NIH HHS / United States HHSN268201100006C / HL / NHLBI NIH HHS / United States HHSN268201100007C / HL / NHLBI NIH HHS / United States HHSN268201100008C / HL / NHLBI NIH HHS / United States HHSN268201100009C / HL / NHLBI NIH HHS / United States HHSN268201100010C / HL / NHLBI NIH HHS / United States HHSN268201100011C / HL / NHLBI NIH HHS / United States HHSN268201100012C / HL / NHLBI NIH HHS / United States |