|Title||Diet Pattern and Respiratory Morbidity in the Atherosclerosis Risk in Communities Study.|
|Publication Type||Journal Article|
|Year of Publication||2018|
|Authors||Brigham EP, Steffen LM, London SJ, Boyce D, Diette GB, Hansel NN, Rice J|
|Secondary Authors||McCormack MC|
|Journal||Ann Am Thorac Soc|
|Date Published||2018 06|
|Keywords||Atherosclerosis, Cross-Sectional Studies, Diet, Female, Follow-Up Studies, Forced Expiratory Volume, Humans, Lung, Male, Middle Aged, Morbidity, Pulmonary Disease, Chronic Obstructive, Retrospective Studies, Risk Factors, Survival Rate, United States, Vital Capacity|
RATIONALE: Dietary intake is a potential risk factor for respiratory morbidity in adult populations. Few studies capture the effect of dietary patterns, representative of the combination of nutrients consumed, on self-reported respiratory morbidity in combination with objective measures of lung function.
OBJECTIVES: To evaluate patterns of dietary intake in relation to respiratory morbidity and objective measures of lung function in a U.S.
METHODS: The ARIC (Atherosclerosis Risk in Communities) study investigators enrolled 15,792 participants from four U.S. communities between 1987 and 1989 and collected data using a validated food frequency questionnaire to assess diet. Principal component analysis was applied, and patterns representative of "Western" and "Prudent" diets emerged. We investigated cross-sectional associations between dietary patterns and pulmonary assessments that included asthma and chronic obstructive pulmonary disease (COPD) diagnosis, respiratory symptoms, and lung function. Multivariable Poisson regression models included quintiles of dietary patterns and potential confounders. Interaction of dietary patterns with obesity, sex, and smoking status was assessed in relation to all outcomes.
RESULTS: Higher scores in the "Western" dietary pattern (quintile 5 vs. quintile 1) were associated with higher prevalence of COPD (prevalence ratio [PR], 1.62; 95% confidence ratio [CI], 1.33-1.97), wheeze (PR, 1.37; 95% CI, 1.11-1.69), cough (PR, 1.32; 95% CI, 1.32-1.59), and phlegm (PR, 1.27; 95% CI, 1.05-1.54) and lower percent predicted forced expiratory volume in 1 second (FEV), percent predicted forced vital capacity (FVC), and FEV/FVC ratio. Higher scores in the "Prudent" dietary pattern (quintile 5 vs. quintile 1) were associated with lower prevalence of COPD (PR, 0.82; 95% CI, 0.70-0.95) and cough (PR, 0.77; 95% CI, 0.67-0.89) and higher percent predicted FEV and FEV/FVC ratio. The prevalence of asthma was not related to dietary intake.
CONCLUSIONS: A "Western" dietary pattern was associated with respiratory symptoms, lower lung function, and COPD in ARIC participants.
|Alternate Journal||Ann Am Thorac Soc|
|PubMed Central ID||PMC6137676|
|Grant List||HHSN268201100012C / HL / NHLBI NIH HHS / United States |
P50 MD010431 / MD / NIMHD NIH HHS / United States
HHSN268201100009I / HL / NHLBI NIH HHS / United States
HHSN268201100010C / HL / NHLBI NIH HHS / United States
HHSN268201100008C / HL / NHLBI NIH HHS / United States
HHSN268201100005G / HL / NHLBI NIH HHS / United States
HHSN268201100008I / HL / NHLBI NIH HHS / United States
HHSN268201100007C / HL / NHLBI NIH HHS / United States
HHSN268201100011I / HL / NHLBI NIH HHS / United States
HHSN268201100011C / HL / NHLBI NIH HHS / United States
F32 HL120396 / HL / NHLBI NIH HHS / United States
HHSN268201100006C / HL / NHLBI NIH HHS / United States
HHSN268201100005I / HL / NHLBI NIH HHS / United States
HHSN268201100009C / HL / NHLBI NIH HHS / United States
HHSN268201100005C / HL / NHLBI NIH HHS / United States
HHSN268201100007I / HL / NHLBI NIH HHS / United States
KL2 TR001077 / TR / NCATS NIH HHS / United States
P50 ES018176 / ES / NIEHS NIH HHS / United States