|Title||Coffee Consumption and Incident Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Study.|
|Publication Type||Journal Article|
|Year of Publication||2018|
|Authors||Hu EA, Selvin E, Grams ME, Steffen LM, Coresh JJ|
|Secondary Authors||Rebholz CM|
|Journal||Am J Kidney Dis|
|Date Published||2018 08|
|Keywords||Atherosclerosis, Coffee, Cohort Studies, Female, Follow-Up Studies, Glomerular Filtration Rate, Humans, Incidence, Male, Middle Aged, Prospective Studies, Renal Insufficiency, Chronic, Residence Characteristics, Risk Factors|
BACKGROUND: Moderate coffee consumption has been suggested to be associated with lower risk for chronic conditions such as diabetes, a major precursor to chronic kidney disease (CKD). However, the association between coffee and CKD has not been fully established. STUDY DESIGN: Prospective cohort study.
SETTING & PARTICIPANTS: 14,209 participants aged 45 to 64 years from the Atherosclerosis Risk in Communities (ARIC) Study.
PREDICTORS: Coffee consumption (cups per day) was assessed at visits 1 (1987-1989) and 3 (1993-1995) using food frequency questionnaires.
OUTCOMES: Incident CKD defined as estimated glomerular filtration rate
RESULTS: There were 3,845 cases of incident CKD over a median of 24 years of follow-up. Men, whites, current smokers, and participants without comorbid conditions were more likely to consume higher amounts of coffee per day. After adjustment for demographic, clinical, and dietary factors, higher categories of coffee consumption were associated with lower risk for incident CKD compared with those who never consumed coffee (HR for
LIMITATIONS: Self-reported coffee consumption and observational design.
CONCLUSIONS: Participants who drank higher amounts of coffee had lower risk for incident CKD after adjusting for covariates. Coffee consumers may not be at adverse risk for kidney disease.
|Alternate Journal||Am J Kidney Dis|
|PubMed Central ID||PMC6057809|
|Grant List||R01 DK089174 / DK / NIDDK NIH HHS / United States |
K01 DK107782 / DK / NIDDK NIH HHS / United States
T32 HL007024 / HL / NHLBI NIH HHS / United States
HHSN268201700001I / HL / NHLBI NIH HHS / United States
K24 DK106414 / DK / NIDDK NIH HHS / United States
HHSN268201700004I / HL / NHLBI NIH HHS / United States
HHSN268201000021C / HL / NHLBI NIH HHS / United States
HHSN268201700002I / HL / NHLBI NIH HHS / United States
HHSN268201700005I / HL / NHLBI NIH HHS / United States
HHSN268201700003I / HL / NHLBI NIH HHS / United States