Pulse lineResearch With Heart Logo

Association of Variants with Blood Pressure in the Atherosclerosis Risk in Communities Study.

TitleAssociation of Variants with Blood Pressure in the Atherosclerosis Risk in Communities Study.
Publication TypeJournal Article
Year of Publication2019
AuthorsBryant TS, Duggal P, Yu B, Morrison AC, Shafi T, Ehret G, Franceschini N, Boerwinkle E, Coresh JJ
Secondary AuthorsTin A
JournalInt J Hypertens
Volume2019
Pagination2137629
Date Published2019
ISSN2090-0384
Abstract

[] encodes dimethylaniline monooxygenase [N-oxide-forming] 3, which breaks down nitrogen-containing compounds, and has been implicated in blood pressure regulation. Studies have reported conflicting results of the association of a common nonsynonymous variant, E158K (rs2266782), with hypertension. We examined the associations of E158K, along with rare and low frequency exonic variants (minor allele frequency [MAF]

DOI10.1155/2019/2137629
Alternate JournalInt J Hypertens
PubMed ID30906589
PubMed Central IDPMC6397986