Title | Association of Midlife Hypertension with Late-Life Hearing Loss. |
Publication Type | Journal Article |
Year of Publication | 2019 |
Authors | Reed NS, Huddle MG, Betz J, Power MC, Pankow JS, Gottesman R, Sharrett ARichey, Mosley TH, Lin FR |
Secondary Authors | Deal JA |
Journal | Otolaryngol Head Neck Surg |
Volume | 161 |
Issue | 6 |
Pagination | 996-1003 |
Date Published | 2019 12 |
ISSN | 1097-6817 |
Keywords | Age Factors, Aged, Aged, 80 and over, Audiometry, Pure-Tone, Blood Pressure, Female, Hearing Loss, Humans, Hypertension, Longitudinal Studies, Male, Middle Aged, Prospective Studies |
Abstract | OBJECTIVE: To investigate the association of midlife hypertension with late-life hearing impairment. STUDY DESIGN: Data from the Atherosclerosis Risk in Communities study, an ongoing prospective longitudinal population-based study (baseline, 1987-1989). SETTING: Washington County, Maryland, research field site. SUBJECTS AND METHODS: Subjects included 248 community-dwelling men and women aged 67 to 89 years in 2013. Systolic blood pressure (SBP) and diastolic blood pressure were measured at each of 5 study visits from 1987-1989 to 2013. Hypertension was defined by elevated systolic or diastolic blood pressure or antihypertensive medication use. A 4-frequency (0.5-4 kHz) better-hearing ear pure tone average in decibels hearing loss (dB HL) was calculated from pure tone audiometry measured in 2013. A cutoff of 40 dB HL was used to indicate clinically significant moderate to severe hearing impairment. Hearing thresholds at 5 frequencies (0.5-8 kHz) were also considered separately. RESULTS: Forty-seven participants (19%) had hypertension at baseline (1987-1989), as opposed to 183 (74%) in 2013. The SBP association with late-life pure tone average differed by the time of measurement, with SBP measured at earlier visits associated with poorer hearing; the difference in pure tone average per 10-mm Hg SBP measured was 1.43 dB HL (95% CI, 0.32-2.53) at baseline versus -0.43 dB HL (95% CI, -1.41 to 0.55) in 2013. Baseline hypertension was associated with higher thresholds (poorer hearing) at 4 frequencies (1, 2, 4, 8 kHz). CONCLUSION: Midlife SBP was associated with poorer hearing measured 25 years later. Further analysis into the longitudinal relationship between hypertension and hearing impairment is warranted. |
DOI | 10.1177/0194599819868145 |
Alternate Journal | Otolaryngol Head Neck Surg |
PubMed ID | 31382849 |
PubMed Central ID | PMC7262678 |
Grant List | HHSN268201100012C / HL / NHLBI NIH HHS / United States HHSN268201100009I / HL / NHLBI NIH HHS / United States U01 HL096812 / HL / NHLBI NIH HHS / United States HHSN268201100010C / HL / NHLBI NIH HHS / United States HHSN268201100008C / HL / NHLBI NIH HHS / United States HHSN268201700001I / HL / NHLBI NIH HHS / United States HHSN268201100007C / HL / NHLBI NIH HHS / United States HHSN268201100011I / HL / NHLBI NIH HHS / United States HHSN268201100011C / HL / NHLBI NIH HHS / United States HHSN268201700004I / HL / NHLBI NIH HHS / United States HHSN268201100006C / HL / NHLBI NIH HHS / United States HHSN268201700002I / HL / NHLBI NIH HHS / United States HHSN268201100005I / HL / NHLBI NIH HHS / United States K01 AG054693 / AG / NIA NIH HHS / United States HHSN268201700003I / HL / NHLBI NIH HHS / United States HHSN268201100007I / HL / NHLBI NIH HHS / United States HHSN268201100005G / HL / NHLBI NIH HHS / United States HHSN268201100008I / HL / NHLBI NIH HHS / United States K23 DC011279 / DC / NIDCD NIH HHS / United States HHSN268201700005I / HL / NHLBI NIH HHS / United States HHSN268201100009C / HL / NHLBI NIH HHS / United States HHSN268201100005C / HL / NHLBI NIH HHS / United States |