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Dietary patterns and risk of incident chronic kidney disease: the Atherosclerosis Risk in Communities study.

TitleDietary patterns and risk of incident chronic kidney disease: the Atherosclerosis Risk in Communities study.
Publication TypeJournal Article
Year of Publication2019
AuthorsHu EA, Steffen LM, Grams ME, Crews DC, Coresh JJ, Appel LJ
Secondary AuthorsRebholz CM
JournalAm J Clin Nutr
Volume110
Issue3
Pagination713-721
Date Published2019 09 01
ISSN1938-3207
KeywordsAtherosclerosis, Diet, Diet, Healthy, Female, Follow-Up Studies, Humans, Male, Middle Aged, Renal Insufficiency, Chronic, Risk Factors
Abstract

BACKGROUND: Adherence to healthy dietary patterns, measured by the Healthy Eating Index (HEI), Alternative Healthy Eating Index (AHEI), and alternate Mediterranean diet (aMed) scores, is associated with a reduced risk of cardiovascular disease. The association between these scores and chronic kidney disease (CKD) is undetermined.

OBJECTIVE: We aimed to estimate the association between the HEI, AHEI, and aMed scores and risk of incident CKD.

METHODS: We conducted a prospective analysis in 12,155 participants aged 45-64 y from the Atherosclerosis Risk in Communities (ARIC) Study. We calculated HEI-2015, AHEI-2010, and aMed scores for each participant and categorized them into quintiles of each dietary score. Incident CKD was defined as an estimated glomerular filtration rate

RESULTS: There were 3980 cases of incident CKD over a median follow-up of 24 y. Participants who had higher adherence to the HEI-2015, AHEI-2010, and aMed scores were more likely to be female, have higher educational attainment, higher income level, be nonsmokers, more physically active, and diabetic compared with participants who scored lower. All 3 dietary scores were associated with lower CKD risk (P-trendĀ 

CONCLUSION: Higher adherence to healthy dietary patterns during middle age was associated with lower risk of CKD.

DOI10.1093/ajcn/nqz146
Alternate JournalAm J Clin Nutr
PubMed ID31386145
PubMed Central IDPMC6736122
Grant ListT32 HL007024 / HL / NHLBI NIH HHS / United States
HHSN268201700001I / HL / NHLBI NIH HHS / United States
HHSN268201700004I / HL / NHLBI NIH HHS / United States
K01 DK107782 / DK / NIDDK NIH HHS / United States
HHSN268201700002I / HL / NHLBI NIH HHS / United States
HHSN268201700003I / HL / NHLBI NIH HHS / United States
K24 HL148181 / HL / NHLBI NIH HHS / United States
R21 HL143089 / HL / NHLBI NIH HHS / United States
HHSN268201700005I / HL / NHLBI NIH HHS / United States