Title | Cardiac structure and function and leisure-time physical activity in the elderly: The Atherosclerosis Risk in Communities Study. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Hegde SM, Gonçalves A, Claggett B, Evenson KR, Cheng S, Shah AM, Folsom AR |
Secondary Authors | Solomon SD |
Journal | Eur Heart J |
Volume | 37 |
Issue | 32 |
Pagination | 2544-51 |
Date Published | 2016 Aug 21 |
ISSN | 1522-9645 |
Keywords | Aged, Atherosclerosis, Cross-Sectional Studies, Diastole, Exercise, Humans, Leisure Activities |
Abstract | AIMS: Adults who engage in leisure-time physical activity (LTPA) have a reduced risk of developing heart failure. We hypothesized that high levels of LTPA are associated with diminished adverse age-related changes in cardiac structure and function. METHODS AND RESULTS: We studied 4342 Atherosclerosis Risk in Communities Study participants free of cardiovascular disease who underwent standardized echocardiography. In a cross-sectional analysis, we related LTPA (poor, intermediate, or ideal) to cardiac structure and function. We also related cumulative average LTPA over 24 years and changes in LTPA categories to echocardiographic measures. Cross-sectional analysis demonstrated that ideal LTPA, compared with poor LTPA, was associated with better diastolic function [prevalence of normal diastolic function: 39.8% vs. 31.5%, P CONCLUSION: Ideal LTPA, higher average levels of LTPA over a 24-year period, and an improvement in LTPA even later in life were associated with more favourable indices of LV diastolic and systolic function in older adults. Sustaining higher levels of LTPA, and even increasing physical activity later in life, may be beneficial for older adults in attenuating expected age-related changes in cardiac structure and function. |
DOI | 10.1093/eurheartj/ehw121 |
Alternate Journal | Eur Heart J |
PubMed ID | 27071820 |
PubMed Central ID | PMC5008418 |
Grant List | T32 HL094301 / HL / NHLBI NIH HHS / United States HHSN268201100007C / HL / NHLBI NIH HHS / United States HHSN268201100006C / HL / NHLBI NIH HHS / United States HHSN268201100008C / HL / NHLBI NIH HHS / United States R00 HL107642 / HL / NHLBI NIH HHS / United States HHSN268201100009C / HL / NHLBI NIH HHS / United States HHSN268201100010C / HL / NHLBI NIH HHS / United States HHSN268201100012C / HL / NHLBI NIH HHS / United States K08 HL116792 / HL / NHLBI NIH HHS / United States HHSN268201100011C / HL / NHLBI NIH HHS / United States HHSN268201100005C / HL / NHLBI NIH HHS / United States |