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Cardiac structure and function and leisure-time physical activity in the elderly: The Atherosclerosis Risk in Communities Study.

TitleCardiac structure and function and leisure-time physical activity in the elderly: The Atherosclerosis Risk in Communities Study.
Publication TypeJournal Article
Year of Publication2016
AuthorsHegde SM, Gonçalves A, Claggett B, Evenson KR, Cheng S, Shah AM, Folsom AR
Secondary AuthorsSolomon SD
JournalEur Heart J
Volume37
Issue32
Pagination2544-51
Date Published2016 Aug 21
ISSN1522-9645
KeywordsAged, Atherosclerosis, Cross-Sectional Studies, Diastole, Exercise, Humans, Leisure Activities
Abstract

AIMS: Adults who engage in leisure-time physical activity (LTPA) have a reduced risk of developing heart failure. We hypothesized that high levels of LTPA are associated with diminished adverse age-related changes in cardiac structure and function.

METHODS AND RESULTS: We studied 4342 Atherosclerosis Risk in Communities Study participants free of cardiovascular disease who underwent standardized echocardiography. In a cross-sectional analysis, we related LTPA (poor, intermediate, or ideal) to cardiac structure and function. We also related cumulative average LTPA over 24 years and changes in LTPA categories to echocardiographic measures. Cross-sectional analysis demonstrated that ideal LTPA, compared with poor LTPA, was associated with better diastolic function [prevalence of normal diastolic function: 39.8% vs. 31.5%, P

CONCLUSION: Ideal LTPA, higher average levels of LTPA over a 24-year period, and an improvement in LTPA even later in life were associated with more favourable indices of LV diastolic and systolic function in older adults. Sustaining higher levels of LTPA, and even increasing physical activity later in life, may be beneficial for older adults in attenuating expected age-related changes in cardiac structure and function.

DOI10.1093/eurheartj/ehw121
Alternate JournalEur Heart J
PubMed ID27071820
PubMed Central IDPMC5008418
Grant ListT32 HL094301 / HL / NHLBI NIH HHS / United States
HHSN268201100007C / HL / NHLBI NIH HHS / United States
HHSN268201100006C / HL / NHLBI NIH HHS / United States
HHSN268201100008C / HL / NHLBI NIH HHS / United States
R00 HL107642 / HL / NHLBI NIH HHS / United States
HHSN268201100009C / HL / NHLBI NIH HHS / United States
HHSN268201100010C / HL / NHLBI NIH HHS / United States
HHSN268201100012C / HL / NHLBI NIH HHS / United States
K08 HL116792 / HL / NHLBI NIH HHS / United States
HHSN268201100011C / HL / NHLBI NIH HHS / United States
HHSN268201100005C / HL / NHLBI NIH HHS / United States