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Longitudinal Blood Pressure Patterns from Mid-to-Late Life and Late-life Hearing Loss in the Atherosclerosis Risk in Communities Study.

TitleLongitudinal Blood Pressure Patterns from Mid-to-Late Life and Late-life Hearing Loss in the Atherosclerosis Risk in Communities Study.
Publication TypeJournal Article
Year of Publication2021
AuthorsTing J, Jiang K, Du S, Betz J, Reed N, Power MC, Gottesman R, A Sharrett R, Griswold M, Walker KA, Miller ERaymond, Lin FR, Deal JA
JournalJ Gerontol A Biol Sci Med Sci
Date Published2021 May 27
ISSN1758-535X
Abstract

BACKGROUND: Hearing loss is prevalent and associated with adverse functional outcomes in older adults. Prevention thus has far-reaching implications, yet few modifiable risk factors have been identified. Hypertension may contribute to age-related hearing loss, but epidemiologic evidence is mixed. We studied a prospective cohort of 3,343 individuals from the Atherosclerosis Risk in Communities study, aged 44-65 years at baseline with up to 30 years of follow-up.

METHODS: Hearing was assessed in late-life (2016-17) using a better-ear audiometric pure tone average (PTA, 0.5, 1, 2, 4 kHz) and the Quick Speech-in-Noise (QuickSIN) test. Hypertension was defined as systolic blood pressure ≥140 mmHg, diastolic blood pressure ≥90 mmHg or antihypertensive medication use. Mid-life hypertension was defined by hypertension at two consecutive visits between 1987-89 and 1996-98. Late-life hypertension was defined in 2016-17. Late-life low blood pressure was defined as systolic blood pressure

RESULTS: Compared to persistent normotension, persistent hypertension from mid-to-late-life was associated with worse central auditory processing (difference in QuickSIN score = -0.66 points, 95% CI: -1.14, -0.17) but not with audiometric hearing.

CONCLUSIONS: Participants with persistent hypertension had poorer late-life central auditory processing. These findings suggest that hypertension may be more strongly related to hearing-related changes in the brain than in the cochlea.

DOI10.1093/gerona/glab153
Alternate JournalJ Gerontol A Biol Sci Med Sci
PubMed ID34043799