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Associations Between Atrial Arrhythmias and Brain Amyloid Deposition: The ARIC-PET Study.

TitleAssociations Between Atrial Arrhythmias and Brain Amyloid Deposition: The ARIC-PET Study.
Publication TypeJournal Article
Year of Publication2022
AuthorsJohansen MC, Wang W, Zhang MJ, Alonso A, Wong DF, Gottesman RF, Chen LY
JournalJ Alzheimers Dis
Date Published2022 Jan 04
ISSN1875-8908
Abstract

The aim of this study is to determine if there is an association between atrial arrhythmias and brain amyloid-β (Aβ), measured on florbetapir (FBP) PET. 346 nondemented participants from the Atherosclerosis Risk in Communities study underwent FBP-PET, 185 also wore Zio® XT Patch. The associations between global cortical Aβ (>  1.2 standardized uptake value ratio) and history of atrial fibrillation, zio-defined atrial tachycardia and premature atrial contractions, each, were evaluated. Among nondemented community-dwelling older adults, we did not find an association between atrial arrhythmias and Aβ. Other brain pathology may underlie the association described between atrial arrhythmias and cognition.

DOI10.3233/JAD-215378
Alternate JournalJ Alzheimers Dis
PubMed ID35001894