Clark DW, Okada Y, Moore KHS, et al. "Associations of autozygosity with a broad range of human phenotypes." Nat Commun. 2019;10(1):4957.: 31673082 : PMC6823371 |
Mitchell RN, Ashar FN, Jarvelin M-R, et al. "Effect of Sex and Underlying Disease on the Genetic Association of QT Interval and Sudden Cardiac Death." J Am Heart Assoc. 2019;8(23):e013751.: 31747862 : PMC6912973 |
Pendergrass SA, Buyske S, Jeff JM, et al. "A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans." PLoS One. 2019;14(12):e0226771.: 31891604 : PMC6938343 |
Huang T, Wang T, Zheng Y, et al. "Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study." JAMA Netw Open. 2019;2(9):e1910915.: 31539074 : PMC6755534 |
Irvin MR, Sitlani CM, Noordam R, et al. "Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry." Pharmacogenomics J. 2019;19(1):97-108.: 29855607 : PMC6274589 |
Morris AP, Le TH, Wu H, et al. "Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies." Nat Commun. 2019;10(1):29.: 30604766 : PMC6318312 |
Spracklen CN, Karaderi T, Yaghootkar H, et al. "Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology." Am J Hum Genet. 2019;105(1):15-28.: 31178129 : PMC6612516 |
Wojcik GL, Graff M, Nishimura KK, et al. "Genetic analyses of diverse populations improves discovery for complex traits." Nature. 2019;570(7762):514-518.: 31217584 : PMC6785182 |
Shungin D, Haworth S, Divaris K, et al. "Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data." Nat Commun. 2019;10(1):2773.: 31235808 : PMC6591304 |
Sikdar S, Joehanes R, Joubert BR, et al. "Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking." Epigenomics. 2019;11(13):1487-1500.: 31536415 : PMC6836223 |
Huan T, Joehanes R, Song C, et al. "Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease." Nat Commun. 2019;10(1):4267.: 31537805 : PMC6753136 |
Liu Y, Chen S, Li Z, Morrison AC, Boerwinkle E. "ACAT: A Fast and Powerful p Value Combination Method for Rare-Variant Analysis in Sequencing Studies." Am J Hum Genet. 2019;104(3):410-421.: 30849328 : PMC6407498 |
Turcot V, Lu Y, Highland HM, et al. "Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity." Nat Genet. 2019;51(7):1191-1192.: 31160809 |
Bien SA, Wojcik GL, Hodonsky CJ, et al. "The Future of Genomic Studies Must Be Globally Representative: Perspectives from PAGE." Annu Rev Genomics Hum Genet. 2019;20:181-200.: 30978304 : PMC7012212 |
Evangelou E, Gao H, Chu C, et al. "New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders." Nat Hum Behav. 2019;3(9):950-961.: 31358974 |
Syme C, Shin J, Richer L, Gaudet D, Fornage M, Paus T. "Epigenetic Loci of Blood Pressure." Circ Genom Precis Med. 2019;12(1):e002341.: 30645168 |
Coresh JJ, Heerspink HJL, Sang Y, et al. "Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies." Lancet Diabetes Endocrinol. 2019;7(2):115-127.: 30635225 : PMC6379893 |
Matsushita K, Sang Y, Ning H, et al. "Lifetime Risk of Lower-Extremity Peripheral Artery Disease Defined by Ankle-Brachial Index in the United States." J Am Heart Assoc. 2019;8(18):e012177.: 31500474 : PMC6818002 |
Agha G, Mendelson MM, Ward-Caviness CK, et al. "Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease." Circulation. 2019;140(8):645-657.: 31424985 : PMC6812683 |
Mishra A, Chauhan G, Violleau M-H, et al. "Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects." Brain. 2019;142(4):1009-1023.: 30859180 : PMC6439324 |
Petty LE, Highland HM, Gamazon ER, et al. "Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample." Hum Mol Genet. 2019;28(7):1212-1224.: 30624610 : PMC6423424 |
Merino J, Guasch-Ferré M, Ellervik C, et al. "Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis." BMJ. 2019;366:l4292.: 31345923 : PMC6652797 |
Chauhan G, Adams HHH, Satizabal CL, et al. "Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting." Neurology. 2019.: 30651383 : PMC6369905 |
Flannick J, Mercader JM, Fuchsberger C, et al. "Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls." Nature. 2019;570(7759):71-76.: 31118516 : PMC6699738 |
Justice AE, Karaderi T, Highland HM, et al. "Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution." Nat Genet. 2019;51(3):452-469.: 30778226 : PMC6560635 |
van Setten J, Verweij N, Mbarek H, et al. "Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits." Eur J Hum Genet. 2019;27(6):952-962.: 30679814 : PMC6777533 |
Kraja AT, Liu C, Fetterman JL, et al. "Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits." Am J Hum Genet. 2019;104(1):112-138.: 30595373 : PMC6323610 |
Ma Y, Jun GR, Zhang X, et al. "Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype." JAMA Neurol. 2019.: 31180460 : PMC6563544 |
Kunkle BW, Grenier-Boley B, Sims R, et al. "Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing." Nat Genet. 2019;51(3):414-430.: 30820047 : PMC6463297 |
Larsson SC, Traylor M, Burgess S, Boncoraglio GB, Jern C, Michaëlsson K. "Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study." Neurology. 2019;92(9):e944-e950.: 30804065 : PMC6404465 |
Lin BM, Nadkarni GN, Tao R, et al. "Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study." Front Genet. 2019;10:494.: 31178898 : PMC6544117 |
Yu B, Zanetti KA, Temprosa M, et al. "The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies." Am J Epidemiol. 2019;188(6):991-1012.: 31155658 : PMC6545286 |
Wuttke M, Li Y, Li M, et al. "A catalog of genetic loci associated with kidney function from analyses of a million individuals." Nat Genet. 2019;51(6):957-972.: 31152163 : PMC6698888 |
Gregson J, Kaptoge S, Bolton T, et al. "Cardiovascular Risk Factors Associated With Venous Thromboembolism." JAMA Cardiol. 2019;4(2):163-173.: 30649175 : PMC6386140 |
de Vries PS, Sabater-Lleal M, Huffman JE, et al. "A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology." Blood. 2019;133(9):967-977.: 30642921 : PMC6396174 |
Sabater-Lleal M, Huffman JE, de Vries PS, et al. "Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels." Circulation. 2019;139(5):620-635.: 30586737 : PMC6438386 |
Naj AC, Lin H, Vardarajan BN, et al. "Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project." Genomics. 2019;111(4):808-818.: 29857119 : PMC6397097 |
Oelsner EC, Balte PP, Grams ME, et al. "Albuminuria, Lung Function Decline, and Risk of Incident Chronic Obstructive Pulmonary Disease. The NHLBI Pooled Cohorts Study." Am J Respir Crit Care Med. 2019;199(3):321-332.: 30261735 : PMC6363973 |
Sarnowski C, Leong A, Raffield LM, et al. "Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program." Am J Hum Genet. 2019;105(4):706-718.: 31564435 : PMC6817529 |
He KY, Li X, Kelly TN, et al. "Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data." Hum Genet. 2019;138(2):199-210.: 30671673 : PMC6404531 |
Kowalski MH, Qian H, Hou Z, et al. "Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations." PLoS Genet. 2019;15(12):e1008500.: 31869403 : PMC6953885 |
Chen H, Huffman JE, Brody JA, et al. "Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies." Am J Hum Genet. 2019;104(2):260-274.: 30639324 : PMC6372261 |
Liang J, Cade BE, He KY, et al. "Sequencing Analysis at 8p23 Identifies Multiple Rare Variants in DLC1 Associated with Sleep-Related Oxyhemoglobin Saturation Level." Am J Hum Genet. 2019;105(5):1057-1068.: 31668705 : PMC6849112 |
Wang SY, Tan ASL, Claggett B, et al. "Longitudinal Associations Between Income Changes and Incident Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." JAMA Cardiol. 2019;4(12):1203-1212.: 31596441 : PMC6802267 |
Georgakis MK, Malik R, Björkbacka H, et al. "Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals." Circ Res. 2019;125(8):773-782.: 31476962 : PMC6763364 |
Parikh RR, Folsom AR, Misialek JR, Rosamond WD, Chang PP, Tang W. "Prospective study of plasma high molecular weight kininogen and prekallikrein and incidence of coronary heart disease, ischemic stroke and heart failure." Thromb Res. 2019;182:89-94.: 31473403 : PMC6825898 |
Pandey A, Patel KV, Vongpatanasin W, et al. "Incorporation of Biomarkers Into Risk Assessment for Allocation of Antihypertensive Medication According to the 2017 ACC/AHA High Blood Pressure Guideline: A Pooled Cohort Analysis." Circulation. 2019;140(25):2076-2088.: 31707797 |
Juraschek SP, Daya N, Appel LJ, et al. "Subclinical Cardiovascular Disease and Fall Risk in Older Adults: Results From the Atherosclerosis Risk in Communities Study." J Am Geriatr Soc. 2019;67(9):1795-1802.: 31493355 : PMC6733582 |
Liu J, Carnero-Montoro E, van Dongen J, et al. "An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis." Nat Commun. 2019;10(1):2581.: 31197173 : PMC6565679 |
Shukla A, Reed N, Armstrong NM, Lin FR, Deal JA. "Hearing Loss, Hearing Aid Use and Depressive Symptoms in Older Adults - Findings from the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." J Gerontol B Psychol Sci Soc Sci. 2019.: 31628485 |
Oyenuga AO, Folsom AR, Cheng S, Tanaka H. "Greater Adherence to Life's Simple 7 Is Associated With Less Arterial Stiffness: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2019;32(8):769-776.: 31090885 : PMC6636696 |
Folsom AR, Lutsey PL, Misialek JR. "A prospective study of migraine history and venous thromboembolism in older adults." Res Pract Thromb Haemost. 2019;3(3):357-363.: 31294322 : PMC6611375 |
George KM, Lutsey PL, Selvin E, Palta P, Windham BGwen. "Association Between Thyroid Dysfunction and Incident Dementia in the Atherosclerosis Risk in Communities Neurocognitive Study." J Endocrinol Metab. 2019;9(4):82-89.: 32411312 : PMC7223793 |
Weinstein G, Davis-Plourde KL, Conner S, et al. "Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts." PLoS One. 2019;14(2):e0212293.: 30768625 : PMC6377188 |
Yee SWah, Stecula A, Chien H-C, et al. "Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies." PLoS Genet. 2019;15(9):e1008208.: 31553721 : PMC6760779 |
Hu EA, Steffen LM, Grams ME, Crews DC, Coresh JJ, Appel LJ. "Dietary patterns and risk of incident chronic kidney disease: the Atherosclerosis Risk in Communities study." Am J Clin Nutr. 2019;110(3):713-721.: 31386145 : PMC6736122 |
Kytömaa S, Hegde S, Claggett B, et al. "Association of Influenza-like Illness Activity With Hospitalizations for Heart Failure: The Atherosclerosis Risk in Communities Study." JAMA Cardiol. 2019;4(4):363-369.: 30916717 : PMC6484790 |
Oyenuga AO, Folsom AR, Lutsey PL. "Association of Life's Simple 7 with reduced clinically manifest abdominal aortic aneurysm: The ARIC study." Vasc Med. 2019;24(3):224-229.: 30898044 : PMC6530464 |
Reed NS, Betz JF, Kucharska-Newton AMaria, Lin FR. "Hearing loss and satisfaction with healthcare: An unexplored relationship." J Am Geriatr Soc. 2019;67(3):624-626.: 30512196 : PMC6403017 |
Lindström S, Brody JA, Turman C, et al. "A large-scale exome array analysis of venous thromboembolism." Genet Epidemiol. 2019;43(4):449-457.: 30659681 : PMC6520188 |
Rattani A, Claxton J'NS, Ali MK, Chen LYee, Soliman EZ. "Association and impact of hypertension defined using the 2017 AHA/ACC guidelines on the risk of atrial fibrillation in The Atherosclerosis Risk in Communities study." BMC Cardiovasc Disord. 2019;19(1):262.: 31771509 : PMC6878648 |
Rooney MR, Soliman EZ, Lutsey PL, et al. "Prevalence and Characteristics of Subclinical Atrial Fibrillation in a Community-Dwelling Elderly Population: The ARIC Study." Circ Arrhythm Electrophysiol. 2019;12(10):e007390.: 31607148 : PMC6814387 |
Folsom AR, Tang W, Basu S, Misialek JR, Couper DJ, Heckbert SR. "Plasma Concentrations of High Molecular Weight Kininogen and Prekallikrein and Venous Thromboembolism Incidence in the General Population." Thromb Haemost. 2019;119(5):834-843.: 30780167 : PMC6499653 |
Arora S, Stouffer GA, Kucharska-Newton AMaria, et al. "Twenty Year Trends and Sex Differences in Young Adults Hospitalized With Acute Myocardial Infarction." Circulation. 2019;139(8):1047-1056.: 30586725 : PMC6380926 |
Almuwaqqat Z, O'Neal WT, Norby FL, et al. "Joint Associations of Obesity and NT-proBNP With the Incidence of Atrial Fibrillation in the ARIC Study." J Am Heart Assoc. 2019;8(19):e013294.: 31564186 : PMC6806039 |
Kim H, Caulfield LE, Garcia-Larsen V, Steffen LM, Coresh JJ. "Plant-Based Diets Are Associated With a Lower Risk of Incident Cardiovascular Disease, Cardiovascular Disease Mortality, and All-Cause Mortality in a General Population of Middle-Aged Adults." J Am Heart Assoc. 2019;8(16):e012865.: 31387433 : PMC6759882 |
Kim H, Caulfield LE, Garcia-Larsen V, Steffen LM, Grams ME, Coresh JJ. "Plant-Based Diets and Incident CKD and Kidney Function." Clin J Am Soc Nephrol. 2019;14(5):682-691.: 31023928 : PMC6500948 |
Bhatt SP, Balte PP, Schwartz JE, et al. "Discriminative Accuracy of FEV1:FVC Thresholds for COPD-Related Hospitalization and Mortality." JAMA. 2019;321(24):2438-2447.: 31237643 : PMC6593636 |
Walker KA, Gottesman RF, Wu A, et al. "Systemic inflammation during midlife and cognitive change over 20 years: The ARIC Study." Neurology. 2019;92(11):e1256-e1267.: 30760633 : PMC6511107 |
Folsom AR, Basu S, Hong C-P, Heckbert SR, Lutsey PL, Rosamond WD. "Reasons for Differences in the Incidence of Venous Thromboembolism in Black Versus White Americans." Am J Med. 2019;132(8):970-976.: 30953632 : PMC6744355 |
Power MC, Su D, Wu A, et al. "Association of white matter microstructural integrity with cognition and dementia." Neurobiol Aging. 2019;83:63-72.: 31585368 : PMC6914220 |
Lee MJeong, Deal JA, Ramulu PY, Sharrett ARichey. "Prevalence of Retinal Signs and Association With Cognitive Status: The ARIC Neurocognitive Study." J Am Geriatr Soc. 2019;67(6):1197-1203.: 30706941 : PMC6698148 |
George KM, Folsom AR, Steffen LM, Wagenknecht LE. "Differences in Cardiovascular Mortality Risk among African Americans in the Minnesota Heart Survey: 1985-2015 vs The Atherosclerosis Risk in Communities Study Cohort: 1987-2015." Ethn Dis. 2019;29(1):47-52.: 30713416 : PMC6343542 |
Porter AK, Schilsky S, Evenson KR, Florido R, Palta P, Holliday KM. "The Association of Sport and Exercise Activities With Cardiovascular Disease Risk: The Atherosclerosis Risk in Communities (ARIC) Study." J Phys Act Health. 2019;16(9):698-705.: 31369998 : PMC6994359 |
Rawlings AM, Sharrett ARichey, Albert MS, et al. "The Association of Late-Life Diabetes Status and Hyperglycemia With Incident Mild Cognitive Impairment and Dementia: The ARIC Study." Diabetes Care. 2019;42(7):1248-1254.: 31221696 : PMC6609963 |
Tin A, Yu B, Ma J, et al. "Reproducibility and Variability of Protein Analytes Measured Using a Multiplexed Modified Aptamer Assay." J Appl Lab Med. 2019;4(1):30-39.: 31639705 : PMC6814271 |
Almuwaqqat Z, Jokhadar M, Norby FL, et al. "Association of Antidepressant Medication Type With the Incidence of Cardiovascular Disease in the ARIC Study." J Am Heart Assoc. 2019;8(11):e012503.: 31140335 : PMC6585369 |
Wu A, Sharrett ARichey, Gottesman RF, et al. "Association of Brain Magnetic Resonance Imaging Signs With Cognitive Outcomes in Persons With Nonimpaired Cognition and Mild Cognitive Impairment." JAMA Netw Open. 2019;2(5):e193359.: 31074810 : PMC6512274 |
Wong E, Ballew SH, Daya N, et al. "Hospitalization Risk among Older Adults with Chronic Kidney Disease." Am J Nephrol. 2019;50(3):212-220.: 31311014 : PMC6726535 |
Walker KA, Sharrett ARichey, Wu A, et al. "Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia." JAMA. 2019;322(6):535-545.: 31408138 : PMC6692677 |
Lu J, Zaimi I, Barber JR, et al. "SES and correlated factors do not explain the association between periodontal disease, edentulism, and cancer risk." Ann Epidemiol. 2019;38:35-41.: 31540766 : PMC6812627 |
Shao IYuefan, Power MC, Mosley T, et al. "Association of Atrial Fibrillation With White Matter Disease." Stroke. 2019;50(4):989-991.: 30879437 : PMC6433530 |
Mounsey LA, Chang PP, Sueta CA, Matsushita K, Russell SD. "In-Hospital and Postdischarge Mortality Among Patients With Acute Decompensated Heart Failure Hospitalizations Ending on the Weekend Versus Weekday: The ARIC Study Community Surveillance." J Am Heart Assoc. 2019;8(15):e011631.: 31319746 : PMC6761634 |
Rawlings AM, Sharrett ARichey, Mosley TH, Wong DF, Knopman DS. "Cognitive Reserve in Midlife is not Associated with Amyloid-β Deposition in Late-Life." J Alzheimers Dis. 2019;68(2):517-521.: 30775981 : PMC6443418 |
Lu Y, Ballew SH, Kwak L, et al. "Physical Activity and Subsequent Risk of Hospitalization With Peripheral Artery Disease and Critical Limb Ischemia in the ARIC Study." J Am Heart Assoc. 2019;8(21):e013534.: 31642360 : PMC6898846 |
Oyenuga A, Folsom AR, Fashanu O, Aguilar D. "Plasma Galectin-3 and Sonographic Measures of Carotid Atherosclerosis in the Atherosclerosis Risk in Communities Study." Angiology. 2019;70(1):47-55.: 29879846 : PMC6239970 |
Loomis SJ, Köttgen A, Li M, et al. "Rare variants in SLC5A10 are associated with serum 1,5-anhydroglucitol (1,5-AG) in the Atherosclerosis Risk in Communities (ARIC) Study." Sci Rep. 2019;9(1):5941.: 30976018 : PMC6459884 |
Cuthbertson CC, Tan X, Heiss G, Kucharska-Newton AMaria, Nichols HB, Kubota Y. "Associations of Leisure-Time Physical Activity and Television Viewing With Life Expectancy Free of Nonfatal Cardiovascular Disease: The ARIC Study." J Am Heart Assoc. 2019;8(18):e012657.: 31495291 : PMC6818021 |
Decker JJ, Norby FL, Rooney MR, et al. "Metabolic Syndrome and Risk of Ischemic Stroke in Atrial Fibrillation: ARIC Study." Stroke. 2019;50(11):3045-3050.: 31623543 : PMC6817422 |