Title | Changes in Bone Mass After Discontinuation of Pre-Exposure Prophylaxis (PrEP) with Tenofovir Disoproxil Fumarate/Emtricitabine in Young Men Who Have Sex With Men: Extension Phase Results of Adolescent Trials Network Protocols 110 and 113 |
Publication Type | Publication |
Year of Publication | 2019 |
Authors | Havens PL, Perumean-Chaney SE, Patki A, Cofield SS, Wilson CM, Liu N, Anderson PL, Landovitz RJ, Kapogiannis BG, Hosek SG, Mulligan K |
Journal | Clin Infect Dis |
Date Published | 2019 Jun 08 |
ISSN | 1537-6591 |
Abstract | HIV-seronegative men who have sex with men aged 15-22 years who lost bone mineral density (BMD) during TDF/FTC PrEP experienced partial or full BMD recovery 48 weeks following PrEP discontinuation, except lumbar spine and whole body BMD Z-scores remained below baseline 48 weeks off PrEP in participants aged 15-19 years. |
DOI | 10.1093/cid/ciz486 |
Alternate Journal | Clin. Infect. Dis. |
PubMed ID | 31179503 |