Safety and Effectiveness of Same-Day Chlamydia trachomatis and Neisseria gonorrhoeae Screening and Treatment Among Gay, Bisexual, Transgender, and Homeless Youth in Los Angeles, California, and New Orleans, Louisiana.

TitleSafety and Effectiveness of Same-Day Chlamydia trachomatis and Neisseria gonorrhoeae Screening and Treatment Among Gay, Bisexual, Transgender, and Homeless Youth in Los Angeles, California, and New Orleans, Louisiana.
Publication TypePublication
Year of Publication2020
AuthorsKeizur EM, Goldbeck C, Vavala G, Romero-Espinoza A, Ocasio M, Fournier J, Lee S-J, Abdalian S-E, Rotheram MJane, Klausner JD
Corporate AuthorsAdolescent Trials Network(ATN) CARES Team
JournalSex Transm Dis
Volume47
Issue1
Pagination19-23
Date Published2020 01
ISSN1537-4521
Abstract

<p><b>BACKGROUND: </b>Gay, bisexual, transgender, and homeless youth are at risk of sexually transmitted infections. As part of an adolescent human immunodeficiency virus prevention study, we provided same-day Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) testing and treatment. We aimed to evaluate the feasibility and effectiveness of same-day CT and NG treatment on the proportion of participants receiving timely treatment.</p><p><b>METHODS: </b>We recruited adolescents with high sexual risk behaviors aged 12 to 24 years from homeless shelters, lesbian, gay, bisexual, and transgender organizations, and community health centers in Los Angeles, California, and New Orleans, Louisiana from May 2017 to June 2019. Initially, participants were offered point-of-care pharyngeal, rectal, and urethral/vaginal CT and NG testing and referral to another clinic for treatment. After March 2018 in Los Angeles and November 2018 in New Orleans, we provided same-day treatment (and partner treatment packs) for study participants. We measured the proportion of participants who received same-day treatment and the median time to treatment. We collected frequency of partner treatment and any reported adverse treatment-related events.</p><p><b>RESULTS: </b>The proportion of participants receiving same-day CT and NG treatment increased from 3.6% (5/140) to 21.1% (20/95; Δ17.5%; 95% confidence interval, 9.2%-26.9%) after implementation of same-day testing and treatment. The median time to treatment decreased from 18.5 to 3 days. Overall, 36 participants took a total of 48 partner treatment packs. There were no reported treatment-related adverse events.</p><p><b>CONCLUSIONS: </b>Providing sexually transmitted infection treatment to adolescents at the same visit as testing is feasible and safe, and can increase the proportion of individuals receiving timely treatment.</p>

DOI10.1097/OLQ.0000000000001088
Alternate JournalSex Transm Dis
PubMed ID31688719
PubMed Central IDPMC6923576
Grant ListP30 MH058107 / MH / NIMH NIH HHS / United States
U19 HD089886 / HD / NICHD NIH HHS / United States
P30 AI028697 / AI / NIAID NIH HHS / United States
UL1 TR001881 / TR / NCATS NIH HHS / United States