Title | Correlates of High HIV Viral Load and Antiretroviral Therapy Adherence Among Viremic Youth in the United States Enrolled in an Adherence Improvement Intervention. |
Publication Type | Publication |
Year of Publication | 2021 |
Authors | K Amico R, Crawford J, Ubong I, Lindsey JC, Gaur AH, Horvath K, Goolsby R, Johnson MMueller, Dallas R, Heckman B, Filipowicz T, Polier M, Rupp BM, Hudgens M |
Journal | AIDS Patient Care STDS |
Volume | 35 |
Issue | 5 |
Pagination | 145-157 |
Date Published | 2021 May |
ISSN | 1557-7449 |
Keywords | Adolescent, Adult, Anti-HIV Agents, HIV Infections, Humans, Medication Adherence, United States, Viral Load, Viremia, Young Adult |
Abstract | <p>A sizable portion of youth (ages 13-24) living with HIV in the United States have unsuppressed viral load. The AIDS Interventions (ATN) 152 study [evaluating the Triggered Escalating Real-Time Adherence (TERA) intervention] baseline data were examined to identify correlates of high viremia (>5000 copies/mL) and self-reported adherence, which can help in planning of differentiated services for viremic youth. Depression, HIV-stigma, and cannabis use were common in this sample of 87 youth. Almost half (48%) had high viremia, which associated with enacted stigma, moderate- to high-risk alcohol use, mental health diagnosis, and age ≥21. Self-reported adherence was related to viral load and associated with mental and physical health functioning, depression, social support, self-confident decision-making, total and internalized stigma, adherence motivation, and report of a missed a care visit in the past 6 months. Mental health emerged as a common correlate of viral load and adherence. Clinical Trial Registration number: NCT03292432.</p> |
DOI | 10.1089/apc.2021.0005 |
Alternate Journal | AIDS Patient Care STDS |
PubMed ID | 33960843 |
PubMed Central ID | PMC8106249 |
Grant List | U24 HD089880 / HD / NICHD NIH HHS / United States |