PrEParing for NextGen: Cognitive Interviews to Improve Next Generation PrEP Modality Descriptions for Young Men Who have Sex with Men.

TitlePrEParing for NextGen: Cognitive Interviews to Improve Next Generation PrEP Modality Descriptions for Young Men Who have Sex with Men.
Publication TypePublication
Year of Publication2022
AuthorsBiello KB, Valente PK, Lin WY, Ii WLodge, Drab R, Hightow-Weidman L, da Silva DTeixeira, Mayer K, Bauermeister JA
JournalAIDS Behav
Volume26
Issue6
Pagination1956-1965
Date Published2022 Jun
ISSN1573-3254
KeywordsAdolescent, Adult, Cognition, HIV Infections, Homosexuality, Male, Humans, Male, Pre-Exposure Prophylaxis, Sexual and Gender Minorities, Young Adult
Abstract

<p>Next generation PrEP formulations may circumvent factors that impede daily oral pre-exposure prophylaxis (PrEP) use among young men who have sex with men (YMSM). We conducted video-based cognitive interviews with 20 YMSM (age 16-24) recruited in the US Northeast to assess participants' attitudes and comprehension of written descriptions of next generation PrEP modalities. Participants were predominately racial/ethnic minorities and half used daily oral PrEP. We identified four main areas for improvement of descriptions: defining scientific terms and balancing medical jargon and casual language; referencing more established products to contextualize PrEP formulations (e.g., hormonal implants); ensuring clarity and reducing redundancy; and including imagery (e.g., rectal douche applicator). The refined descriptions serve as exemplar text that may be used in future studies examining YMSM's preferences across next generation PrEP modalities. Accurate descriptions of next generation PrEP products strengthen measurement accuracy and can help roll-out products that become approved for clinical use.</p>

DOI10.1007/s10461-021-03545-w
Alternate JournalAIDS Behav
PubMed ID34860304
PubMed Central IDPMC9050851
Grant ListT32 HS026116 / HS / AHRQ HHS / United States
U19 HD089881 / HD / NICHD NIH HHS / United States
U19HD089881 / / eunice kennedy shriver national institute of child health and human development /
T32 HS026116-03 / / agency for healthcare research and quality /