Improving comprehension for HIV vaccine trial information among adolescents at risk of HIV.

TitleImproving comprehension for HIV vaccine trial information among adolescents at risk of HIV.
Publication TypePublication
Year of Publication2007
AuthorsMurphy DA, Hoffman D, Seage GR, Belzer M, Xu J, Durako SJ, Geiger M
Corporate AuthorsAdolescent Trials Network for HIV/AIDS Interventions
JournalAIDS Care
Date Published2007 Jan
KeywordsAdolescent, Adult, AIDS Vaccines, Comprehension, Feasibility Studies, Female, Focus Groups, Health Knowledge, Attitudes, Practice, HIV Infections, Humans, Male, Mental Recall, Patient Education as Topic, Psychological Tests, Risk Factors

<p>A simplified version of the HIVNET prototype HIV vaccine process was developed for adolescents at risk of HIV by:(1) reducing reading level; (2) reorganizing; (3) adding illustrations; and (4) obtaining focus group feedback. Then adolescents (N = 187) in three cities were randomly assigned to the standard or simplified version. Adolescents receiving the simplified version had significantly higher comprehension scores (80% correct vs. 72% correct), with 37% of items significantly more likely to be answered correctly. They were also significantly more likely to recall study benefits and procedures. Overall, adolescents were less willing to participate in a potential HIV vaccine trial after presentation than prior to presentation. The present study indicates that it would be feasible for adolescents to participate in a vaccine trial, as simplification of vaccine information, combined with illustrations to depict key concepts, resulted in improved scores for adolescents on the comprehension and recall test.</p>

Alternate JournalAIDS Care
PubMed ID17265577
Grant ListU01 HD040474 / HD / NICHD NIH HHS / United States
U01 HD040533 / HD / NICHD NIH HHS / United States
U01 HD40533 / HD / NICHD NIH HHS / United States