Youth living with HIV and partner-specific risk for the secondary transmission of HIV.

TitleYouth living with HIV and partner-specific risk for the secondary transmission of HIV.
Publication TypePublication
Year of Publication2009
AuthorsJennings JM, Ellen JM, Deeds BGriffin, D Harris R, Muenz LR, Barnes W, Lee SS, Auerswald CL
Corporate AuthorsAdolescent Trials Network for HIV/AIDS Interventions
JournalSex Transm Dis
Volume36
Issue7
Pagination439-44
Date Published2009 Jul
ISSN1537-4521
KeywordsAdolescent, Adolescent Behavior, Adult, Clinical Trials as Topic, Condoms, Cross-Sectional Studies, Female, HIV Infections, Humans, Male, Risk-Taking, Sexual Behavior, Sexual Partners, Substance-Related Disorders, Surveys and Questionnaires, Young Adult
Abstract

<p><b>BACKGROUND: </b>Secondary transmission remains a significant concern among HIV-infected youth. Little is known, however, about how partner-specific sexual risk behaviors for the secondary transmission of HIV may differ between the 2 largest subgroups of HIV-positive youth, women-who-have-sex-with-men (WSM) and men-who-have-sex-with-men (MSM), METHODS: During 2003-2004, a convenience sample of HIV-infected youth, 13 to 24 years of age, were recruited from 15 Adolescent Medicine Trials Network clinical sites. Approximately 10 to 15 youth were recruited at each site. Participants completed an ACASI survey including questions about sex partners in the past year. Cross-sectional data analyses, including bivariate and multivariable regressions, using generalized estimating equations, were conducted during 2008 to compare recent partner-specific sexual risk behaviors between WSM and MSM.</p><p><b>RESULTS: </b>Of 409 participants, 91% (371) were included in this analysis, including 176 WSM and 195 MSM. Ninety-two percent (163 WSM, 177 MSM) provided information on characteristics of their sexual partners. There were significant differences between the 2 groups in recent partner-specific sexual risk behaviors including: lower rates of condom use at last sex among WSM (61% WSM vs. 78% MSM; P = 0.0011); a larger proportion of the sex partners of MSM reported as concurrent (56% MSM vs. 36% WSM; P = 0.0001); and greater use of hard drugs at last sex by MSM and/or their partner (18% MSM vs. 4% WSM; P = 0.0008). When measuring risk as a composite measure of sexual risk behaviors known to be associated with HIV transmission, both groups had high rates of risky behaviors, 74.7% among young MSM compared to 68.1% of WSM.</p><p><b>CONCLUSIONS: </b>These data suggest that recent partner-specific sexual risk behaviors for HIV transmission are high among young infected MSM and WSM. These findings suggest the need to offer interventions to reduce the secondary transmission of HIV to all HIV-positive youth in care. However, differences in risk behaviors between young MSM and WSM supports population-specific interventions.</p>

DOI10.1097/OLQ.0b013e3181ad516c
Alternate JournalSex Transm Dis
PubMed ID19525889
PubMed Central IDPMC2725398
Grant ListU01 HD040533 / HD / NICHD NIH HHS / United States
U01 HD040474 / HD / NICHD NIH HHS / United States
U01 HD040506 / HD / NICHD NIH HHS / United States
H25/CCH222333-01 / / PHS HHS / United States
U01 HD040506-01 / HD / NICHD NIH HHS / United States
U01 HD040533-01 / HD / NICHD NIH HHS / United States
K01 DA022298 / DA / NIDA NIH HHS / United States