Predictors of medication adherence in high risk youth of color living with HIV.

TitlePredictors of medication adherence in high risk youth of color living with HIV.
Publication TypePublication
Year of Publication2010
AuthorsMacdonell KE, Naar-King S, Murphy DA, Parsons JT, Harper GW
JournalJ Pediatr Psychol
Volume35
Issue6
Pagination593-601
Date Published2010 Jul
ISSN1465-735X
KeywordsAdolescent, African Americans, Anti-Retroviral Agents, Chi-Square Distribution, Female, HIV Infections, HIV Seropositivity, Humans, Male, Medication Adherence, Motivation, Social Support, Surveys and Questionnaires, Viral Load, Young Adult
Abstract

<p><b>OBJECTIVE: </b>To test predictors of medication adherence in high-risk racial or ethnic minority youth living with HIV (YLH) using a conceptual model of social cognitive predictors including a continuous measure of motivational readiness.</p><p><b>METHODS: </b>Youth were participants in a multi-site clinical trial examining the efficacy of a motivational intervention. Racial-minority YLH (primarily African American) who were prescribed antiretroviral medication were included (N = 104). Data were collected using computer-assisted personal interviewing method via an Internet-based application and questionnaires.</p><p><b>RESULTS: </b>Using path analysis with bootstrapping, most youth reported suboptimal adherence, which predicted higher viral load. Higher motivational readiness predicted optimal adherence, and higher social support predicted readiness. Decisional balance was indirectly related to adherence.</p><p><b>CONCLUSIONS: </b>The model provided a plausible framework for understanding adherence in this population. Culturally competent interventions focused on readiness and social support may be helpful for improving adherence in YLH.</p>

DOI10.1093/jpepsy/jsp080
Alternate JournalJ Pediatr Psychol
PubMed ID19755495
PubMed Central IDPMC2889251
Grant ListU01 HD040474 / HD / NICHD NIH HHS / United States
U01 HD040533 / HD / NICHD NIH HHS / United States
U01-HD040533 / HD / NICHD NIH HHS / United States