Health related quality of life and psychosocial correlates among HIV-infected adolescent and young adult women in the US.

TitleHealth related quality of life and psychosocial correlates among HIV-infected adolescent and young adult women in the US.
Publication TypePublication
Year of Publication2011
AuthorsAndrinopoulos K, Clum G, Murphy DA, Harper G, Perez L, Xu J, Cunningham S, Ellen JM
Corporate AuthorsAdolescent Medicine Trials Network for HIV/AIDS Interventions
JournalAIDS Educ Prev
Volume23
Issue4
Pagination367-81
Date Published2011 Aug
ISSN1943-2755
KeywordsAdaptation, Physiological, Adolescent, Anxiety, Attitude to Health, CD4 Lymphocyte Count, Depression, Female, Health Status, HIV Infections, Humans, Quality of Life, Regression Analysis, Social Stigma, Social Support, Surveys and Questionnaires, United States, Viral Load, Young Adult
Abstract

<p>In this study HIV health-related quality of life (HIV-HRQOL) is examined among 179 behaviorally infected adolescent and young adult women. Modifiable psychosocial variables including depression, stigma, social support, and illness acceptance, and the biological end-points of CD4 cell count and viral load were explored in relation to HIV-HRQOL. The three factors of the HIV-HRQOL measure include current life satisfaction, illness related anxiety and illness burden. Bivariate linear regression analysis demonstrated statistically significant associations for all psychosocial variables and HIV HRQOL factors (p < .01), but not for biological end-points. In multivariate linear regression analysis significant associations remained between: depression (p = .006), illness acceptance (p < .001), social support (p = .001), and current life satisfaction, and depression (p = .012), illness acceptance (p = .015), and illness burden. A trend in association was noted for HIV stigma, with current life satisfaction and illness related anxiety but did not reach statistical significance (p = .097 and p = .109 respectively). Interventions that effectively decrease stigma and depression and increase social support and illness acceptance will likely improve the well-being and quality of life of HIV-infected adolescent women.</p>

Alternate JournalAIDS Educ Prev
PubMed ID21966746
PubMed Central IDPMC3287350
Grant ListR24 HD042854 / HD / NICHD NIH HHS / United States
U01 HD040533 / HD / NICHD NIH HHS / United States
U01 HD040533-10 / HD / NICHD NIH HHS / United States
U01 HD040474 / HD / NICHD NIH HHS / United States
U01 HD40533 / HD / NICHD NIH HHS / United States
U01 HD040470 / HD / NICHD NIH HHS / United States