Risk perceptions after human papillomavirus vaccination in HIV-infected adolescents and young adult women.

TitleRisk perceptions after human papillomavirus vaccination in HIV-infected adolescents and young adult women.
Publication TypePublication
Year of Publication2012
AuthorsKahn JA, Xu J, Zimet GD, Liu N, Gonin R, Dillard ME, Squires K
Corporate AuthorsAdolescent Trials Network for HIV/AIDS Interventions
JournalJ Adolesc Health
Volume50
Issue5
Pagination464-70
Date Published2012 May
ISSN1879-1972
KeywordsAdolescent, Adult, Female, Health Knowledge, Attitudes, Practice, HIV Infections, Humans, Papillomavirus Infections, Papillomavirus Vaccines, Risk, Sexual Behavior, Sexually Transmitted Diseases, Surveys and Questionnaires, Vaccination, Young Adult
Abstract

<p><b>PURPOSE: </b>To examine risk perceptions (perceived risk of human papillomavirus [HPV], perceived risk of other sexually transmitted infections [STIs], and need for safer sexual behaviors) and to determine factors associated with these risk perceptions after HPV vaccination.</p><p><b>METHODS: </b>Data were collected at the baseline visit of an HPV-6, -11, -16, -18 vaccine clinical trial in 16-23-year-old HIV-infected young women (N = 99). Immediately after receiving the first vaccine dose, participants completed a confidential questionnaire that included three 5-item scales measuring perceived risk of HPV, perceived risk of other STIs, and need for safer sexual behaviors. Linear and logistic regression models were used to examine associations between baseline characteristics (demographic characteristics; cluster of differentiation antigen 4 (CD4(+)) count; HIV viral load; knowledge about HPV and HPV vaccines; sexual behaviors; and STI diagnosis) and each measure of risk perceptions.</p><p><b>RESULTS: </b>Most participants perceived themselves to be at lower risk for HPV (mean scale score = 19.5/50), most perceived that they were not at lower risk for other STIs (mean = 31.2/50), and the vast majority reported that there was still a need for safer sexual behaviors after vaccination (mean = 43.1/50). Multivariate analyses indicated that knowledge about HPV and HPV vaccines was associated with perceived need for safer sexual behaviors (OR = 1.05, 95% CI = 1.0-1.1).</p><p><b>CONCLUSIONS: </b>Although almost all young women in this study believed that safer sexual behaviors were still important after HPV vaccination, a subset believed they were at less risk for STIs other than HPV. Educational interventions are needed to prevent misperceptions and promote healthy behaviors after vaccination.</p>

DOI10.1016/j.jadohealth.2011.09.005
Alternate JournalJ Adolesc Health
PubMed ID22525109
PubMed Central IDPMC3336095
Grant ListU01 HD 040533 / HD / NICHD NIH HHS / United States
U01 HD040533 / HD / NICHD NIH HHS / United States
U01 HD 040474 / HD / NICHD NIH HHS / United States
U01 HD040533-10 / HD / NICHD NIH HHS / United States
U01 HD040474 / HD / NICHD NIH HHS / United States
NCRRUL1-RR-024134 / / PHS HHS / United States
M01RR020359 / RR / NCRR NIH HHS / United States
UL1 RR024134 / RR / NCRR NIH HHS / United States
M01 RR020359 / RR / NCRR NIH HHS / United States