Exploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIV.

TitleExploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIV.
Publication TypePublication
Year of Publication2014
AuthorsRubinstein ML, D Harris R, Rudy BJ, Kapogiannis BG, Aldrovandi GM, Mulligan K
JournalAIDS Res Treat
Volume2014
Pagination740545
Date Published2014
ISSN2090-1240
Abstract

<p>We conducted cross-sectional, multicenter studies in HIV-positive young women and men to assess metabolic and morphologic complications from tobacco smoking in 372 behaviorally infected HIV-positive youth, aged 14-25 years. Measurements included self-reported tobacco use, fasting lipids, glucose, fat distribution, and bone mineral density (BMD; dual-energy X-ray absorptiometry scans). Overall, 144 (38.7%) self-reported smoking tobacco and 69 (47.9%) of these reported smoking greater than five cigarettes per day. Smokers versus nonsmokers had lower mean total cholesterol (146.0 versus 156.1 mg/dL; P < 0.01) and lower mean total body fat percent (24.1% versus 27.2%, P = 0.03). There was no difference between smokers and nonsmokers in fasting glucose or BMD. There appear to be only minimal effects from tobacco smoking on markers of cardiac risk and bone health in this population of HIV-positive youth. While these smokers may not have had sufficient exposure to tobacco to detect changes in the outcome measures, given the long-term risks associated with smoking and HIV, it is critical that we encourage HIV-positive youth smokers to quit before the deleterious effects become apparent. </p>

DOI10.1155/2014/740545
Alternate JournalAIDS Res Treat
PubMed ID25114801
PubMed Central IDPMC4119894
Grant ListU01 HD040533 / HD / NICHD NIH HHS / United States
U01 HD040474 / HD / NICHD NIH HHS / United States
R01 DA036508 / DA / NIDA NIH HHS / United States
UL1 RR024131 / RR / NCRR NIH HHS / United States
R01 CA140216 / CA / NCI NIH HHS / United States
UL1 RR024134 / RR / NCRR NIH HHS / United States
M01 RR020359 / RR / NCRR NIH HHS / United States