A Comparison of Long-Acting Injectable Medications for Schizophrenia

The ACLAIMS study is a multi-center randomized controlled trial of patients with schizophrenia or schizoaffective disorder who are expected to benefit from a long-acting injectable antipsychotic medication.
The study will compare the therapeutic effectiveness, cost-effectiveness, tolerability (incidence and severity of adverse events), and enduring acceptability of two long-acting injectable antipsychotic preparations, paliperidone palmitate (PP) and haloperidol decanoate (HD), over a 2 year period of treatment and follow-up.