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Manuscripts and Publications

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Zhao X, Qiao D, Yang C, Kasela S, Kim W, Ma Y, Shrine N, Batini C, Sofer T, Taliun SAGagliano et al..  2020.  Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants.. Nat Commun. 11(1):5182.
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Sofer T, Emery L, Jain D, Ellis AM, Laurie CC, Allison MA, Lee J, Kurniansyah N, Kerr KF, González HM et al..  2019.  Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos.. Sci Rep. 9(1):11410.
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Mägi R, Horikoshi M, Sofer T, Mahajan A, Kitajima H, Franceschini N, McCarthy MI, Morris AP.  2017.  Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution.. Hum Mol Genet. 26(18):3639-3650.
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Liang J, Le TH, Edwards DRVelez, Tayo BO, Gaulton KJ, Smith JA, Lu Y, Jensen RA, Chen G, Yanek LR et al..  2017.  Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.. PLoS Genet. 13(5):e1006728.
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Sofer T, Moon J-Y, Isasi CR, Qi Q, Shah NA, Kaplan RC, Kuniholm MH.  2018.  Relationship of genetic determinants of height with cardiometabolic and pulmonary traits in the Hispanic Community Health Study/Study of Latinos.. Int J Epidemiol. 47(6):2059-2069.
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Sofer T, Heller R, Bogomolov M, Avery CL, Graff M, North KE, Reiner AP, Thornton TA, Rice K, Benjamini Y et al..  2017.  A powerful statistical framework for generalization testing in GWAS, with application to the HCHS/SOL.. Genet Epidemiol. 41(3):251-258.
Hu X, Qiao D, Kim W, Moll M, Balte PP, Lange LA, Bartz TM, Kumar R, Li X, Yu B et al..  2022.  Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program.. Am J Hum Genet. 109(5):857-870.
Zhou LY, Sofer T, Horimoto ARVR, Talavera GA, Lash JP, Cai J, Franceschini N.  2023.  Polygenic risk scores and kidney traits in the Hispanic/Latino population: The Hispanic Community Health Study/Study of Latinos.. HGG Adv. 4(2):100177.
Granot-Hershkovitz E, He S, Bressler J, Yu B, Tarraf W, Rebholz CM, Cai J, Chan Q, Garcia TP, Mosley T et al..  2023.  Plasma metabolites associated with cognitive function across race/ethnicities affirming the importance of healthy nutrition.. Alzheimers Dement. 19(4):1331-1342.
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Moon J-Y, Wang T, Sofer T, North KE, Isasi CR, Cai J, Gellman MD, Moncrieft AE, Sotres-Alvarez D, Argos M et al..  2017.  Objectively Measured Physical Activity, Sedentary Behavior, and Genetic Predisposition to Obesity in U.S. Hispanics/Latinos: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).. Diabetes. 66(12):3001-3012.
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Chen H, Cade BE, Gleason KJ, Bjonnes AC, Stilp AM, Sofer T, Conomos MP, Ancoli-Israel S, Arens R, Azarbarzin A et al..  2018.  Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea-related Quantitative Trait Locus in Men.. Am J Respir Cell Mol Biol. 58(3):391-401.
Khoury S, Wang Q-P, Parisien M, Gris P, Bortsov AV, Linnstaedt SD, McLean SA, Tungate AS, Sofer T, Lee J et al..  2021.  Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons.. Sleep. 44(3)
Shahu A, Chung J, Tarraf W, Ramos AR, González HM, Redline S, Cai J, Sofer T.  2023.  Method comparison and estimation of causal effects of insomnia on health outcomes in a survey sampled population.. Sci Rep. 13(1):9831.
Zhang Y, Yu B, Qi Q, Azarbarzin A, Chen H, Shah NA, Ramos AR, Zee PC, Cai J, Daviglus ML et al..  2024.  Metabolomic profiles of sleep-disordered breathing are associated with hypertension and diabetes mellitus development.. Nat Commun. 15(1):1845.
Sofer T, Zhang Y, Yu B, Qi Q, Azarbarzin A, Chen H, Shah N, Ramos A, Zee P, Cai J et al..  2023.  Metabolomic Profiles of Sleep-Disordered Breathing are Associated with Hypertension and Diabetes Mellitus Development: the HCHS/SOL.. Res Sq.
Lin BM, Zhang Y, Yu B, Boerwinkle E, Thygarajan B, Yunes M, Daviglus ML, Qi Q, Kaplan R, Lash J et al..  2022.  Metabolome-wide association study of estimated glomerular filtration rates in Hispanics.. Kidney Int. 101(1):144-151.
Sofer T, Shaffer JR, Graff M, Qi Q, Stilp AM, Gogarten SM, North KE, Isasi CR, Laurie CC, Szpiro AA.  2016.  Meta-Analysis of Genome-Wide Association Studies with Correlated Individuals: Application to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).. Genet Epidemiol. 40(6):492-501.
Yan Q, Brehm J, Pino-Yanes M, Forno E, Lin J, Oh SS, Acosta-Perez E, Laurie CC, Cloutier MM, Raby BA et al..  2017.  A meta-analysis of genome-wide association studies of asthma in Puerto Ricans.. Eur Respir J. 49(5)
Li Y, Wong KYau, Howard AGreen, Gordon-Larsen P, Highland HM, Graff M, North KE, Downie CG, Avery CL, Yu B et al..  2024.  Mendelian randomization with incomplete measurements on the exposure in the Hispanic Community Health Study/Study of Latinos.. HGG Adv. 5(1):100245.
Bryan MScannell, Sofer T, Mossavar-Rahmani Y, Thyagarajan B, Zeng D, Daviglus ML, Argos M.  2019.  Mendelian randomization of inorganic arsenic metabolism as a risk factor for hypertension- and diabetes-related traits among adults in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) cohort.. Int J Epidemiol. 48(3):876-886.
Bryan MScannell, Sofer T, Afshar M, Mossavar-Rahmani Y, H Hosgood D, Punjabi NM, Zeng D, Daviglus ML, Argos M.  2021.  Mendelian randomization analysis of arsenic metabolism and pulmonary function within the Hispanic Community Health Study/Study of Latinos.. Sci Rep. 11(1):13470.
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Sung YJ, Winkler TW, Fuentes Lde Las, Bentley AR, Brown MR, Kraja AT, Schwander K, Ntalla I, Guo X, Franceschini N et al..  2018.  A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.. Am J Hum Genet. 102(3):375-400.
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Kurniansyah N, Wallace DA, Zhang Y, Yu B, Cade B, Wang H, Ochs-Balcom HM, Reiner AP, Ramos AR, Smith JD et al..  2023.  An integrated multi-omics analysis of sleep-disordered breathing traits implicates P2XR4 purinergic signaling.. Commun Biol. 6(1):125.
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Joshi PH, Marcovina S, Orroth K, J López AG, Kent ST, Kaplan R, Swett K, Sotres-Alvarez D, Thyagarajan B, Slipczuk L et al..  2023.  Heterogeneity of Lipoprotein(a) Levels Among Hispanic or Latino Individuals Residing in the US.. JAMA Cardiol. 8(7):691-696.
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Méndez-Giráldez R, Gogarten SM, Below JE, Yao J, Seyerle AA, Highland HM, Kooperberg C, Soliman EZ, Rotter JI, Kerr KF et al..  2017.  GWAS of the electrocardiographic QT interval in Hispanics/Latinos generalizes previously identified loci and identifies population-specific signals.. Sci Rep. 7(1):17075.

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