Accessibility issues or difficulties with this website?
Call 919-962-2073 or email hchsadministration@unc.edu.

Metabolic Syndrome in Hispanic Youth: Results from the Hispanic Community Children's Health Study/Study of Latino Youth.

TitleMetabolic Syndrome in Hispanic Youth: Results from the Hispanic Community Children's Health Study/Study of Latino Youth.
Publication TypePublication
Year2017
AuthorsReina SA, Llabre MM, Vidot DC, Isasi CR, Perreira K, Carnethon M, Parrinello CM, Gallo LC, Ayala GX, Delamater A
JournalMetab Syndr Relat Disord
Volume15
Issue8
Pagination400-406
Date Published2017 10
ISSN1557-8518
KeywordsAdolescent, Cardiovascular Diseases, Child, Child Health, Female, Hispanic Americans, Humans, Male, Metabolic syndrome, Nutrition Surveys, Residence Characteristics, Risk Factors
Abstract

BACKGROUND: Metabolic syndrome (MetS), a cluster of cardiovascular risk factors, is being diagnosed in youth. Specific diagnostic criteria used to define MetS influence prevalence estimates and populations considered at risk for cardiovascular disease. The National Cholesterol Education Program's Adult Treatment Panel III (ATP), the World Health Organization (WHO), and the International Diabetes Federation (IDF) provide three MetS definitions used in medical research. This study examined concordance among these definitions in 1137 children 10-16 years of age, who participated in the Hispanic Community Children's Health Study/Study of Latino Youth.METHODS: Prevalence of MetS and of individual components was estimated using SAS. Mplus was used to test a single-factor model of MetS components (triglycerides, high-density lipoprotein cholesterol, systolic and diastolic blood pressure, waist circumference, and fasting glucose).RESULTS: The ATP definition identified most MetS cases in 10-15 (N = 19, 4.7%) and 16-year-old girls (N = 3, 7.3%). The IDF definition identified most cases of MetS in 10-15 (N = 16, 3.1%) and 16-year-old boys (N = 2, 2.8%). Fewest cases of MetS were identified with the WHO definition across age and sex groups.CONCLUSION: Only one participant was classified as having MetS across all three definitions. Confirmatory factor analysis indicated fasting glucose and systolic blood pressure did not reliably cluster with other risk factors that define MetS in Hispanic/Latino adolescents. We conclude that prevalence estimates of MetS in youth are unstable across current criteria, calling into question the accuracy of defining and diagnosing MetS in youth.

DOI10.1089/met.2017.0054
Alternate JournalMetab Syndr Relat Disord
PubMed ID28829223
PubMed Central IDPMC5649400
Grant ListN01HC65236 / HL / NHLBI NIH HHS / United States
T32 HL007426 / HL / NHLBI NIH HHS / United States
N01HC65237 / HL / NHLBI NIH HHS / United States
N01HC65234 / HL / NHLBI NIH HHS / United States
N01HC65235 / HL / NHLBI NIH HHS / United States
N01HC65233 / HL / NHLBI NIH HHS / United States
P30 DK111022 / DK / NIDDK NIH HHS / United States
P2C HD050924 / HD / NICHD NIH HHS / United States
R01 HL102130 / HL / NHLBI NIH HHS / United States
MS#: 
0317
Manuscript Lead/Corresponding Author Affiliation: 
Field Center: Miami (University of Miami)
ECI: 
Yes
Manuscript Status: 
Published