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Periodontal disease and incident prediabetes and diabetes: The Hispanic Community Health Study/Study of Latinos.

TitlePeriodontal disease and incident prediabetes and diabetes: The Hispanic Community Health Study/Study of Latinos.
Publication TypePublication
Year2022
AuthorsLaniado N, Khambaty T, Hua S, Kaplan R, Llabre MM, Schneiderman N, Singer RH, Qi Q, Cai J, Finlayson TL, Whalen AM, Isasi CR
JournalJ Clin Periodontol
Volume49
Issue4
Pagination313-321
Date Published2022 04
ISSN1600-051X
KeywordsDiabetes Mellitus, Hispanic or Latino, Humans, periodontal diseases, Prediabetic State, Public Health, Risk Factors, United States
Abstract

AIM: To examine whether baseline periodontal disease is independently associated with incident prediabetes and incident diabetes in Hispanics/Latinos in the United States.MATERIALS AND METHODS: This study examined 7827 individuals, 18-74 years of age without diabetes, from the Hispanic Community Health Study/Study of Latinos. Participants received a full-mouth periodontal examination at baseline (2008-2011), and the disease was classified using the Centers for Disease Control and Prevention/American Academy of Periodontology case definitions. At Visit 2 (2014-2017), incident prediabetes and diabetes were assessed using multiple standard procedures including blood tests. Multivariable survey Poisson regressions estimated the rate ratio (RR) and 95% confidence intervals (CIs) of incident prediabetes and incident diabetes associated with periodontal disease severity.RESULTS: Among the individuals without prediabetes or diabetes at baseline, 38.8% (n = 1553) had developed prediabetes and 2.2% (n = 87) had developed diabetes after 6 years. Nineteen percent (n = 727) of individuals with prediabetes at baseline developed diabetes after 6 years. Adjusting for all potential confounders, no significant association was found between periodontal disease severity and either incident prediabetes (RR: 0.93; 95% CI: 0.82-1.06) or incident diabetes (RR: 0.99; 95% CI: 0.80-1.22).CONCLUSIONS: Our findings suggest that among a diverse cohort of Hispanic/Latino individuals living in the United States, there was no association between periodontal disease severity and the development of either prediabetes or diabetes during a 6-year follow-up period.

DOI10.1111/jcpe.13599
Alternate JournalJ Clin Periodontol
PubMed ID35112368
PubMed Central IDPMC8934300
Grant ListDK111022-8786 / NH / NIH HHS / United States
N01HC65236 / HL / NHLBI NIH HHS / United States
N01HC65235 / HL / NHLBI NIH HHS / United States
/ NS / NINDS NIH HHS / United States
/ MD / NIMHD NIH HHS / United States
N01-HC65233 / HL / NHLBI NIH HHS / United States
/ DC / NIDCD NIH HHS / United States
N01-HC65237 / HL / NHLBI NIH HHS / United States
/ DE / NIDCR NIH HHS / United States
N01-HC65234 / HL / NHLBI NIH HHS / United States
N01-HC65235 / HL / NHLBI NIH HHS / United States
N01HC65234 / HL / NHLBI NIH HHS / United States
P30 DK111022 / DK / NIDDK NIH HHS / United States
N01HC65233 / HL / NHLBI NIH HHS / United States
N01-HC65236 / HL / NHLBI NIH HHS / United States
N01HC65237 / HL / NHLBI NIH HHS / United States
MS#: 
0531
Manuscript Lead/Corresponding Author Affiliation: 
Field Center: Miami (University of Miami)
ECI: 
Yes
Manuscript Affiliation: 
Field Center: Miami (University of Miami)
Manuscript Status: 
Published