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Prevalence and Correlates of CKD in Hispanics/Latinos in the United States.

TitlePrevalence and Correlates of CKD in Hispanics/Latinos in the United States.
Publication TypePublication
Year2015
AuthorsRicardo AC, Flessner MF, Eckfeldt JH, Eggers PW, Franceschini N, Go AS, Gotman NM, Kramer HJ, Kusek JW, Loehr LR, Melamed ML, Peralta CA, Raij L, Rosas SE, Talavera GA, Lash JP
JournalClin J Am Soc Nephrol
Volume10
Issue10
Pagination1757-66
Date Published2015 Oct 07
ISSN1555-905X
KeywordsAdolescent, Adult, Aged, Cardiovascular Diseases, Central America, Cross-Sectional Studies, Cuba, Diabetes Mellitus, Dominican Republic, European Continental Ancestry Group, Female, Glomerular Filtration Rate, Hispanic Americans, Humans, Male, Mexico, Middle Aged, Nutrition Surveys, Poverty, Prevalence, Prospective Studies, Puerto Rico, Renal Insufficiency, Chronic, Risk Factors, Sex Factors, South America, United States, Young Adult
Abstract

BACKGROUND AND OBJECTIVES: The prevalence of ESRD among Hispanics/Latinos is 2-fold higher than in non-Hispanic whites. However, little is known about the prevalence of earlier stages of CKD among Hispanics/Latinos. This study estimated the prevalence of CKD in US Hispanics/Latinos.DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This was a cross-sectional study of 15,161 US Hispanic/Latino adults of Cuban, Dominican, Mexican, Puerto Rican, Central American, and South American backgrounds enrolled in the multicenter, prospective, population-based Hispanic Community Health Study/Study of Latinos (HCHS/SOL). In addition, the prevalence of CKD in Hispanics/Latinos was compared with other racial/ethnic groups in the 2007-2010 National Health and Nutrition Examination Survey (NHANES). Prevalent CKD was defined as an eGFR <60 ml/min per 1.73 m(2) (estimated with the 2012 Chronic Kidney Disease Epidemiology Collaboration eGFR creatinine-cystatin C equation) or albuminuria based on sex-specific cut points determined at a single point in time.RESULTS: The overall prevalence of CKD among Hispanics/Latinos was 13.7%. Among women, the prevalence of CKD was 13.0%, and it was lowest in persons with South American background (7.4%) and highest (16.6%) in persons with Puerto Rican background. In men, the prevalence of CKD was 15.3%, and it was lowest (11.2%) in persons with South American background and highest in those who identified their Hispanic background as "other" (16.0%). The overall prevalence of CKD was similar in HCHS/SOL compared with non-Hispanic whites in NHANES. However, prevalence was higher in HCHS/SOL men and lower in HCHS/SOL women versus NHANES non-Hispanic whites. Low income, diabetes mellitus, hypertension, and cardiovascular disease were each significantly associated with higher risk of CKD.CONCLUSIONS: Among US Hispanic/Latino adults, there was significant variation in CKD prevalence among Hispanic/Latino background groups, and CKD was associated with established cardiovascular risk factors.

DOI10.2215/CJN.02020215
Alternate JournalClin J Am Soc Nephrol
PubMed ID26416946
PubMed Central IDPMC4594064
Grant ListK24 DK092290 / DK / NIDDK NIH HHS / United States
N01HC65236 / HL / NHLBI NIH HHS / United States
N01HC65235 / HL / NHLBI NIH HHS / United States
N01-HC65237 / HC / NHLBI NIH HHS / United States
N01HC65234 / HL / NHLBI NIH HHS / United States
R01 HL118305 / HL / NHLBI NIH HHS / United States
R21-HL123677-01 / HL / NHLBI NIH HHS / United States
K23-DK094829 / DK / NIDDK NIH HHS / United States
N01HC65233 / HL / NHLBI NIH HHS / United States
K24-DK092290 / DK / NIDDK NIH HHS / United States
1R01-ES021367-01 / ES / NIEHS NIH HHS / United States
N01HC65237 / HL / NHLBI NIH HHS / United States
N01-HC65233 / HC / NHLBI NIH HHS / United States
UL1 TR001073 / TR / NCATS NIH HHS / United States
N01-HC65234 / HC / NHLBI NIH HHS / United States
N01-HC65236 / HC / NHLBI NIH HHS / United States
R21 HL123677 / HL / NHLBI NIH HHS / United States
K23 DK094829 / DK / NIDDK NIH HHS / United States
N01-HC65235 / HC / NHLBI NIH HHS / United States
R01 ES021367 / ES / NIEHS NIH HHS / United States
1R01-HL118305-01A1 / HL / NHLBI NIH HHS / United States
MS#: 
0038
Manuscript Lead/Corresponding Author Affiliation: 
Field Center: Chicago (University of Illinois at Chicago)
ECI: 
Manuscript Affiliation: 
NIH Institution - NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
Manuscript Status: 
Published