Title | Sleep Timing, Stability, and BP in the Sueño Ancillary Study of the Hispanic Community Health Study/Study of Latinos. |
Publication Type | Publication |
Year | 2019 |
Authors | Abbott SM, Weng J, Reid KJ, Daviglus ML, Gallo LC, Loredo JS, Nyenhuis SM, Ramos AR, Shah NA, Sotres-Alvarez D, Patel SR, Zee PC |
Journal | Chest |
Volume | 155 |
Issue | 1 |
Pagination | 60-68 |
Date Published | 2019 Jan |
ISSN | 1931-3543 |
Keywords | actigraphy, Adolescent, Adult, blood pressure, Circadian Rhythm, Cross-Sectional Studies, Female, Follow-Up Studies, Hispanic or Latino, Humans, Incidence, Information Systems, Male, Middle Aged, Prevalence, Public Health, Retrospective Studies, Self Report, sleep, Sleep Initiation and Maintenance Disorders, Time Factors, United States, Young Adult |
Abstract | BACKGROUND: Timing and stability of the sleep-wake cycle are potential modifiable risk factors for cardiometabolic disease. The aim of this study was to evaluate the relationship between objective measures of sleep-wake timing and stability with cardiometabolic disease risk.METHODS: In this multicenter, cross-sectional, population-based study, actigraphy data were obtained from the 2,156 adults, aged 18 to 64 years, recruited from the Sueño ancillary study of the Hispanic Community Health Study/Study of Latinos (2010-2013). These data were correlated with measures of cardiometabolic disease risk, including systolic and diastolic BPs, homeostatic assessment of insulin resistance, glycosylated hemoglobin, BMI, and hypertension and diabetes status.RESULTS: Each 10% decrease in interdaily stability was associated with a 3.0% absolute increase in the prevalence of hypertension (95% CI, 0.6-5.3; P < .05), an increase in systolic BP by 0.78 mm Hg (95% CI, 0.12-1.45; P < .05) and an increase in diastolic BP by 0.80 mm Hg (95% CI, 0.28-1.32; P < .05). In addition, delaying the midpoint of sleep by 1 h was associated with an increase in systolic BP by 0.73 mm Hg (95% CI, 0.30-1.16; P < .01) and diastolic BP by 0.53 mm Hg (95% CI, 0.17-0.90; P < .01). These associations were not significant after adjusting for shift work status. No association was found between interdaily stability or sleep timing and diabetes, BMI, or insulin resistance.CONCLUSIONS: These results suggest that beyond sleep duration, the timing and regularity of sleep-wake schedules are related to hypertension prevalence and BP. |
DOI | 10.1016/j.chest.2018.09.018 |
Alternate Journal | Chest |
PubMed ID | 30300651 |
PubMed Central ID | PMC6344384 |
Grant List | K24 HL127307 / HL / NHLBI NIH HHS / United States N01HC65236 / HL / NHLBI NIH HHS / United States N01HC65235 / HL / NHLBI NIH HHS / United States N01HC65234 / HL / NHLBI NIH HHS / United States R21 HL140437 / HL / NHLBI NIH HHS / United States R01 HL140580 / HL / NHLBI NIH HHS / United States N01HC65237 / HL / NHLBI NIH HHS / United States R21 AG056952 / AG / NIA NIH HHS / United States P30 DK111022 / DK / NIDDK NIH HHS / United States N01HC65233 / HL / NHLBI NIH HHS / United States P01 AG011412 / AG / NIA NIH HHS / United States R01 HL098297 / HL / NHLBI NIH HHS / United States |
Sleep Timing, Stability, and BP in the Sueño Ancillary Study of the Hispanic Community Health Study/Study of Latinos.
MS#:
0280
ECI:
Yes
Manuscript Affiliation:
Field Center: Chicago (University of Illinois at Chicago)
Manuscript Status:
Published