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Prevalence of atrial fibrillation and association with clinical, sociocultural, and ancestral correlates among Hispanic/Latinos: The Hispanic Community Health Study/Study of Latinos.

TitlePrevalence of atrial fibrillation and association with clinical, sociocultural, and ancestral correlates among Hispanic/Latinos: The Hispanic Community Health Study/Study of Latinos.
Publication TypePublication
Year2019
AuthorsLinares JD, Jackson LR, Dawood FZ, Swett K, Benjamin EJ, Schneiderman N, Soliman EZ, Cai J, Alonso A, Wassertheil-Smoller S, Talavera GA, Daubert JP, Daviglus ML, Rodriguez CJ
JournalHeart Rhythm
Volume16
Issue5
Pagination686-693
Date Published2019 May
ISSN1556-3871
KeywordsAdolescent, Adult, Aged, Atrial Fibrillation, Female, Follow-Up Studies, Hispanic or Latino, Humans, Male, Middle Aged, Prevalence, Prospective Studies, Public Health, Risk Assessment, Risk Factors, United States, Young Adult
Abstract

BACKGROUND: Hispanics/Latinos represent the largest ethnic minority group in the United States. Atrial fibrillation (AF) is the most common cardiac arrhythmia in the United States.OBJECTIVE: The purpose of this study was to provide data on the prevalence of AF and its correlates in a representative Hispanic/Latino population-based sample inclusive of all background groups.METHODS: Hispanic Community Health Study/Study of Latinos participants (n=16,415; 60% women; 59% age >45 years) were enrolled between March 2008 and June 2011, representing individuals of Cuban, Dominican, Mexican, Puerto Rican, Central American, and South American heritage. AF was defined by the 12-lead electrocardiogram and/or participant self-report of a physician diagnosis. Hispanic background-specific AF prevalence rates were determined. Weighted sequential logistic regression models were adjusted for demographic factors (age and sex) and clinical variables (diabetes, hypertension, body mass index, tobacco use, and estimated glomerular filtration rate).RESULTS: The overall weighted prevalence of AF was 1.0% (n=162), with the highest prevalence in Hispanics of Dominican and Puerto Rican backgrounds (1.9% and 2.5% respectively) and the lowest in those of Mexican background (0.3%). Diabetes, hypertension, renal disease, left ventricular hypertrophy determined by the electrocardiogram, alcohol use, and English language preference (greater acculturation) (P < .01 for all) were significantly associated with higher AF prevalence. Multivariate analysis by Hispanic/Latino background group showed that Hispanics of Dominican and Puerto Rican backgrounds were at a 3- to 6-fold higher risk of AF than their Mexican counterparts.CONCLUSION: In a diverse representative population of Hispanics/Latinos, overall AF prevalence was low and varied significantly across Hispanic/Latino background groups independent of clinical or demographic factors.

DOI10.1016/j.hrthm.2018.11.033
Alternate JournalHeart Rhythm
PubMed ID31036248
PubMed Central IDPMC7603898
Grant ListR56 HL104199 / HL / NHLBI NIH HHS / United States
R01 HL104199 / HL / NHLBI NIH HHS / United States
N01HC65236 / HL / NHLBI NIH HHS / United States
N01HC65235 / HL / NHLBI NIH HHS / United States
N01HC65234 / HL / NHLBI NIH HHS / United States
N01HC65233 / HL / NHLBI NIH HHS / United States
N01HC65237 / HL / NHLBI NIH HHS / United States
T32 HL125294 / HL / NHLBI NIH HHS / United States
16EIA26410001 / AHA_ / American Heart Association-American Stroke Association / United States
MS#: 
0304
Manuscript Lead/Corresponding Author Affiliation: 
Field Center: Bronx (Einstein College of Medicine)
ECI: 
Yes
Manuscript Status: 
Published