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The cross-sectional association of cognitive stimulation factors and cognitive function among Latino adults in Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

TitleThe cross-sectional association of cognitive stimulation factors and cognitive function among Latino adults in Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
Publication TypePublication
Year2019
AuthorsVásquez PM, Tarraf W, Doza A, Marquine MJ, Perreira KM, Schneiderman N, Zeng D, Cai J, Isasi CR, Daviglus ML, González HM
JournalAlzheimers Dement (N Y)
Volume5
Pagination533-541
Date Published2019
ISSN2352-8737
Abstract

Introduction: Higher cognitive stimulation (CS) is associated with improved cognition. Sources of CS among Hispanics/Latinos are understudied.Methods: In the Hispanic Community Health Study/Study of Latinos 2008 to 2011 ( = 9438), we used finite mixture models to generate latent CS profiles, and multivariate linear regressions to examine associations with cognition in Hispanic/Latino adults (45-74 years). CS included education, occupation, social network, and acculturation. Cognitive measures included the Six-Item Screener, Brief-Spanish English Verbal Learning Test Sum and Recall, Controlled Oral Word Association Test, Digit Symbol Substitution, and Global Cognition.Results: Two CS profiles emerged, and were labeled "typical" and "enhanced." The enhanced CS profile (22%) had more family connections, bicultural engagements, skilled/professional occupations, education, and higher cognitive scores.Discussion: An enhanced CS profile emerged from contextual and culturally relevant factors, and was associated with higher cognitive scores across all measures. This provides initial evidence on how factors coalesce to shape cognitive protection in Hispanics/Latinos.

DOI10.1016/j.trci.2019.07.006
Alternate JournalAlzheimers Dement (N Y)
PubMed ID31650010
PubMed Central IDPMC6804586
Grant ListP30 AG059299 / AG / NIA NIH HHS / United States
R01 AG048642 / AG / NIA NIH HHS / United States
N01HC65236 / HL / NHLBI NIH HHS / United States
N01HC65235 / HL / NHLBI NIH HHS / United States
N01HC65234 / HL / NHLBI NIH HHS / United States
N01HC65233 / HL / NHLBI NIH HHS / United States
N01HC65237 / HL / NHLBI NIH HHS / United States
MS#: 
0712
Manuscript Lead/Corresponding Author Affiliation: 
Affiliated Investigator - Not at HCHS/SOL site
ECI: 
Yes
Manuscript Affiliation: 
HCHS/SOL Baseline Visit - Neurocognitive Reading Center
Manuscript Status: 
Published