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Cognition and Daily Functioning: Results from the Hispanic Community Health Study/Study of Latinos (SOL) and Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).

TitleCognition and Daily Functioning: Results from the Hispanic Community Health Study/Study of Latinos (SOL) and Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).
Publication TypePublication
Year2020
AuthorsStickel AM, Tarraf W, Wu B, Marquine MJ, Vásquez PM, Daviglus M, Estrella ML, Perreira KM, Gallo LC, Lipton RB, Isasi CR, Kaplan R, Zeng D, Schneiderman N, González HM
JournalJ Alzheimers Dis
Volume77
Issue3
Pagination1267-1278
Date Published2020
ISSN1875-8908
KeywordsActivities of Daily Living, Aged, aging, Cognition, Cohort Studies, executive function, Female, Hispanic Americans, Humans, Male, Mental Status and Dementia Tests, Middle Aged, Neuropsychological Tests, Prospective Studies, Public Health, Self Report
Abstract

BACKGROUND: Among older adults, poorer cognitive functioning has been associated with impairments in instrumental activities of daily living (IADLs). However, IADL impairments among older Hispanics/Latinos is poorly understood.OBJECTIVE: To characterize the relationships between cognition and risk for IADL impairment among diverse Hispanics/Latinos.METHODS: Participants included 6,292 community-dwelling adults from the Study of Latinos - Investigation of Neurocognitive Aging, an ancillary study of 45+ year-olds in the Hispanic Community Health Study/Study of Latinos. Cognitive data (learning, memory, executive functioning, processing speed, and a Global cognitive composite) were collected at Visit 1. IADL functioning was self-reported 7 years later, and treated as a categorical (i.e., risk) and continuous (i.e., degree) measures of impairment. Survey two-part models (mixture of logit and generalized linear model with Gaussian distribution) and ordered logistic regression tested the associations of cognitive performance (individual tests and composite z-score) with IADL impairment. Additionally, we investigated the moderating role of age, sex, and Hispanic/Latino background on the association between cognition and IADL impairment.RESULTS: Across all cognitive measures, poorer performance was associated with higher odds of IADL impairment 7 years later. Associations were generally stronger for the oldest group (70+ years) relative to the youngest group (50-59 years). Sex and Hispanic/Latino background did not modify the associations. Across the full sample, lower scores on learning, memory, and the Global cognitive composite were also associated with higher degree of IADL impairment.CONCLUSION: Across diverse Hispanics/Latinos, cognitive health is an important predictor of everyday functioning 7 years later, especially in older adulthood.

DOI10.3233/JAD-200502
Alternate JournalJ Alzheimers Dis
PubMed ID32831203
PubMed Central IDPMC7945678
Grant ListN01 HC065234 / HC / NHLBI NIH HHS / United States
N01HC65236 / HL / NHLBI NIH HHS / United States
N01HC65233 / HL / NHLBI NIH HHS / United States
N01 HC065236 / HC / NHLBI NIH HHS / United States
N01 HC065235 / HC / NHLBI NIH HHS / United States
L60 MD015551 / MD / NIMHD NIH HHS / United States
P30 AG066615 / AG / NIA NIH HHS / United States
P30 AG059299 / AG / NIA NIH HHS / United States
R01 AG048642 / AG / NIA NIH HHS / United States
RF1 AG061022 / AG / NIA NIH HHS / United States
N01HC65235 / HL / NHLBI NIH HHS / United States
P30 AG062429 / AG / NIA NIH HHS / United States
R56 AG048642 / AG / NIA NIH HHS / United States
RF1 AG054548 / AG / NIA NIH HHS / United States
N01 HC065237 / HC / NHLBI NIH HHS / United States
N01HC65234 / HL / NHLBI NIH HHS / United States
N01HC65237 / HL / NHLBI NIH HHS / United States
N01 HC065233 / HC / NHLBI NIH HHS / United States
MS#: 
0938
ECI: 
Manuscript Status: 
Published