Title | Joint associations of insomnia and sleep duration with prevalent diabetes: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL). |
Publication Type | Publication |
Year | 2016 |
Authors | Cespedes EM, Dudley KA, Sotres-Alvarez D, Zee PC, Daviglus ML, Shah NA, Talavera GA, Gallo LC, Mattei J, Qi Q, Ramos AR, Schneiderman N, Espinoza-Giacinto RA, Patel SR |
Journal | J Diabetes |
Volume | 8 |
Issue | 3 |
Pagination | 387-97 |
Date Published | 2016 May |
ISSN | 1753-0407 |
Keywords | Adolescent, Adult, Aged, Cross-Sectional Studies, Diabetes Mellitus, Type 2, Female, Hispanic or Latino, Humans, Male, Middle Aged, Obesity, Prevalence, Risk Factors, Sleep Initiation and Maintenance Disorders, United States, Young Adult |
Abstract | BACKGROUND: Inadequate sleep quantity and quality are associated with a higher risk of type 2 diabetes. This relationship is not well-examined in U.S. Hispanics/Latinos, and prior analyses may be confounded by sleep apnea. This cross-sectional study examined joint associations of sleep duration and insomnia with diabetes among diverse U.S. Hispanic/Latinos.METHODS: Baseline data on sleep quantity and quality were obtained from 15,227 participants (mean age 41; range 18-74 years) from the Hispanic Community Health Study/Study of Latinos. Complex survey multinomial logistic regression was used to examine associations between prevalent diabetes and six phenotypes defined by cross-classifying sleep duration (short ≤6 h, average >6-9 h, long >9 h) and insomnia, adjusting for sex, age, site and Hispanic/Latino background interaction, education, physical activity, diet quality, and sleep apnea.RESULTS: In the weighted population, 14% had diabetes, 28% had insomnia, 9% were short sleepers, and 19% were long sleepers. Compared with those with average sleep and no insomnia, those with short sleep and insomnia were more likely to have diabetes (odds ratio [OR] 1.46; 95% confidence interval [CI] 1.02, 2.11). Average sleepers with insomnia (1.28; 95% CI 1.02, 1.61) and long sleepers without insomnia (1.33; 95% CI 1.07, 1.65) also had elevated odds of diabetes. Further adjustment for body mass index attenuated associations, except with long sleep without insomnia.CONCLUSIONS: Both decreased quantity and quality of sleep are associated with diabetes in Hispanic/Latinos, with the greatest odds among those with short sleep duration and insomnia. The association is largely explained by obesity. |
DOI | 10.1111/1753-0407.12308 |
Alternate Journal | J Diabetes |
PubMed ID | 25952169 |
PubMed Central ID | PMC5021506 |
Grant List | N01 HC065234 / HC / NHLBI NIH HHS / United States KL2 TR000461 / TR / NCATS NIH HHS / United States K01 HL120951 / HL / NHLBI NIH HHS / United States K23 HL125923 / HL / NHLBI NIH HHS / United States N01HC65236 / HL / NHLBI NIH HHS / United States N01HC65235 / HL / NHLBI NIH HHS / United States N01 HC065237 / HC / NHLBI NIH HHS / United States N01-HC65237 / HC / NHLBI NIH HHS / United States N01HC65234 / HL / NHLBI NIH HHS / United States N01HC65233 / HL / NHLBI NIH HHS / United States N01HC65237 / HL / NHLBI NIH HHS / United States N01-HC65233 / HC / NHLBI NIH HHS / United States N01 HC065236 / HC / NHLBI NIH HHS / United States T32-DK007703 / DK / NIDDK NIH HHS / United States N01-HC65234 / HC / NHLBI NIH HHS / United States N01-HC65236 / HC / NHLBI NIH HHS / United States T32 DK007703 / DK / NIDDK NIH HHS / United States N01 HC065235 / HC / NHLBI NIH HHS / United States N01-HC65235 / HC / NHLBI NIH HHS / United States |
Joint associations of insomnia and sleep duration with prevalent diabetes: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
MS#:
0255
ECI:
Yes
Manuscript Status:
Published