Projects

Project Name Clinical Centers Participants Study Design Beginning Ending Funding
A Comparison of Long-Acting Injectable Medications for Schizophrenia (ACLAIMS) 25 360 Randomized, double-masked comparative effectiveness clinical trial Columbia Univ, NIMH
Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN)
ARIC Carotid MRI (CARMRI) 4 2,066 Cross-sectional and prospective design NHLBI
ARIC MRI and Neurocognitive Longitudinal Study (ARIC MRI) 2 1,134 Prospective cohort follow-up NHLBI
ARIC Neurocognitive Study (ARIC-NCS) 4 8,600 Observational study NHLBI
Asymptomatic Carotid Atherosclerosis Study (ACAS) 37 1,500 Randomized, unmasked trial
Atherosclerosis Risk in Communities (ARIC) 4 15,792 Prospective cohort follow-up NHLBI
Back Pain Consortium Research Program (BACPAC) NIAMS
Bronchiectasis Research Registry (BRON) 11 Patient Registry COPD Foundation
Cholesterol Reduction in Seniors Program (CRISP) 5 400 Randomized, double-masked pilot study NHLBI
Combining Medications and Behavioral Interventions (COMBINE) 11 1,380 Randomized 2x2x2 factorial trial NIAAA
Comparison of Antipsychotics for Metabolic Problems (CAMP) 26 300 Randomized, open-label placebo-controlled clinical trial NHLBI
Comparison of Depression Interventions after Acute Coronary Syndrome (CODIACS) 5 150 Randomized, single-masked clinical trial NHLBI
Comparison of Optimal Antipsychotic Treatments for Schizophrenia (COATS) 15 90 Randomized, open-label clinical trial NIMH
Dietary Effects on Lipoproteins and Thrombogenic Activity (DELTA, DELTA-1, DELTA-2) 4 103, 85 2 Randomized, double-masked trials NHLBI
Enhancing Recovery in Coronary Heart Disease (ENRICHD) 8 2,481 Randomized, unmasked trial NHLBI
Epidemiologic Studies of Glargine Use and Cancer Risk (DIMS-ESGUCR) Multi-site retropspective study Sanofi-Aventis
Extremely Low Gestational Age Newborns (ELGAN) 12 8,000 Observational Study NICHD
Fluvastatin Registration Program (FRP) 68 2,000 7 Randomized, double-masked trials, open-label safety study
Hispanic Community Health Study / Study of Latinos (HCHS-SOL) 4 16,000 Population-based prospective cohort follow-up NHLBI
Hispanic Community Health Study / Study of Latinos Youth Study (HCHS-SOLY) 4 1,600 Cross-sectional observational study NHLBI
International Studies of CVD (INTL) 7 20,000 4 prospective cohort follow-up, randomized, unmasked trials NHLBI
Jackson Heart Study Advisory Coordinating Center (JHS) 1 6,500 Prospective cohort follow-up, family genetic study NHLBI
Laser Induced, Biologically Engineered Remodeling of Thermally Injured Skin Trial (LIBERTI)
Lipid Research Clinics Program (LRC) 16 116,800 Prevalence Study, Prospective cohort follow-up, Randomized, double-masked trial, Family genetics study NHLBI
Longitudinal Studies of Child Abuse and Neglect (LONGSCAN) 5 1,400 Prospective cohort follow-up NCCAN
Maternal Oral Therapy to Reduce Obstetric Risk (MOTOR) 3 1,800 Randomized, unmasked trial NIDCR
Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD) 9 1,200 Randomized double masked placebo controlled clinical trial NICHD
Metformin in Treatment of Antipsychotic-Induced Weight Gain in Schizophrenia (METS) 17 80 Randomized, double-masked placebo-controlled trial NIMH
MOTOR Kids (MOTORKIDS) 3 332 Observational study NIDCR
National Strategy for Environment and Health, United Arab Emirates (UAEE) 600 Population survey Environmental Agency - Abu Dhabi
Obesity Prevention in Native American Indians (PATHWAYS) 4 1,700 Community randomized, single-masked trial NHLBI
Periodontal treatment to Eliminate Minority Inequality and Rural disparities in Stroke (PREMIERS) 0 0
Periodontitis and Vascular Events (PAVE) 5 3,000 Randomized pilot study University of Buffalo
Precision Interventions for Severe and/or Exacerbation-Prone Asthma Network (PrecISE) 10 800 Clinical Trial NHLBI
Predicting Responses to Standardized Pediatric Colitis Therapy (PROTECT) 24 430 Multicenter open-label clinical trial Univ Connecticut, NIDDK
Randomized Intervention in Children with VesicoUreteral Reflux (RIVUR) 15 600 Randomized, double-masked controlled clinical trial NIDDK
Studies of Left Ventricular Dysfunction (SOLVD) 28 6,300 2 Randomized, double-masked trials NHLBI
Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) 12 3,200 Observational study NHLBI and COPD Foundation
Trial of Activity for Adolescent Girls (TAAG) 6 10,000 2-arm group randomized trial NHLBI
Trial of Surgery & Thrombolysis in Ischemia of the Lower Extremity (STILE) 34 400 Randomized, unmasked trial NHLBI
Vitamin Intervention for Stroke Prevention (VISP) 56 3,600 Randomized, double-masked trial NHLBI
Women's Health Initiative (WHI) 4,700 Observational study and clinical trials Fred Hutchinson Cancer Inst., NHLBI